Role of Salbutamol in The Management of Transient Tachypnea of the Newborn: A Comparative Prospective Study

  • Waqas Ahmed Combined Military Hospital Dera Ismial Khan/National University of Medical Science (NUMS) Rawalpindi Pakistan
  • Ali Mujtaba Tahir Combined Military Hospital Zhob/ National University of Medical Science (NUMS) Rawalpindi Pakistan
  • Fahim Ahmed Subhani Islamic International Medical College Riphah Pakistan
  • Zeeshan Ahmed Pak Emirates Military Hospital/National University of Medical Science (NUMS) Rawalpindi Pakistan
  • Amina Sohail Combined Military Hospital/National University of Medical Science (NUMS) Rawalpindi Pakistan
  • Hafsa Javed Bahria University Islamabad Pakistan
Keywords: Nebulization, Normal saline, Respiratory rate, Salbutamol, Transient tachypnea of the newborn

Abstract

Objective: To compare the outcome of Salbutamol nebulization with normal saline (placebo) in transient tachypnea of the newborn.

Study Design: Comparative prospective study.

Place and Duration of Study: Department of Neonatal Medicine, Military Hospital Rawalpindi, from Jan 2017 to Mar 2018.

Methodology: Sixty term neonates with respiratory rate >60 breaths/min and transient tachypnea of newborn score of ≥4 were enrolled. They were randomly allocated to two equal groups. Group-1 received Salbutamol nebulization (0.15 mg/kg) while Group-2 received normal Saline (placebo) nebulization.

Results: The mean gestational age was 38.31±1.28 weeks, while the average birth weight was 2.97±0.27 kg. The mean change in transient tachypnea of newborn score with Salbutamol nebulization was 5.63±1.22, while 0.63±1.54 with normal Saline nebulization. Likewise, the mean change in respiratory rate with Salbutamol was 9.80±2.05, while -3.73±2.57 with normal saline.

Conclusion: This study demonstrated nebulized Salbutamol as an effective tool in reversing transient tachypnea of newborns with decreasing respiratory rate compared to normal saline nebulization (placebo).

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Published
2022-10-30
How to Cite
Ahmed, W., Tahir, A., Subhani, F., Ahmed, Z., Sohail, A., & Javed, H. (2022). Role of Salbutamol in The Management of Transient Tachypnea of the Newborn: A Comparative Prospective Study. Pakistan Armed Forces Medical Journal, 72(5), 1501-05. https://doi.org/10.51253/pafmj.v72i5.4746
Section
Original Articles