Comparing the Efficacy of Dexmedetomidine and Meperidine in the Prevention of Post-Spinal Shivering in Patients Undergoing Cesarean Section

Saquib  Naeem; Sajjad  Ahmed; Sumbal  Rana; Ali Arslan  Munir; Iftikhar  Ahmed; Muhammad Amim  Akhter

doi:10.51253/pafmj.v75i6.9724

Authors

Saquib Naeem Department of Ophthalmology, Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Sajjad Ahmed Department of Ophthalmology, Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Sumbal Rana Department of Ophthalmology, Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Ali Arslan Munir Department of Ophthalmology, Combined Military Hospital Bahawalpur/National University of Medical Sciences (NUMS) Pakistan
Iftikhar Ahmed Department of Ophthalmology, Combined Military Hospital Malir/National University of Medical Sciences (NUMS) Pakistan
Muhammad Amim Akhter Department of Ophthalmology, Combined Military Hospital Quetta/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i6.9724

Keywords:

Caesarean Section, Dexmedetomidine, Meperidine, Spinal Anesthesia

Abstract

Objective: To compare the effectiveness of Dexmedetomidine and Meperidine in prevention of post-spinal shivering in patients undergoing caesarean section.

Study Design: Quasi-experimental study.

Place and Duration of Study: Department of Anaesthesia, Combined Military Hospital, Bahawalpur Pakistan, from Jan to Jun 2022.

Methodology: One hundred patients between 18-40 years of age, ASA class II and III, undergoing elective cesarean section were observed by taking 50 patients in each group. Both groups were randomly allocated for pretreatment to either receive the 2ml of intravenous dose of 0.5ug/kg dexmedetomidine (Group-A) or 0.5mg/kg Meperidine (Group-B). Incidence of shivering at 0, 15 and 30 minutes, severity of shivering according to Tsai and Chu grade and requirements of rescue drug were noted.

Results: The shivering scores measured at 0, 15 and 30 minutes showed p-values of 0.07, 0.303 and 0.500, which were not significant for both groups. The groups were comparable to each other in terms of age as mean age in Group-A was 28.44±4.23 while it was 28.06±4.32 years in Group-B. Mean weight for Group-A was 73.32±7.69 kg, whereas it was 72.1±7.45 kg for Group-B. Rescue drug was not required in both Dexmedetomidine and Meperidine groups.

Conclusion: Intravenous dexmedetomidine (in the dose of 0.5ug/kg) is equally effective in preventing the post spinal shivering, in patients undergoing caesarean section as compared to intravenous meperidine (0.5mg/kg dose).

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