OBSTETRIC AND PERINATAL OUTCOME IN INDUCTION OF LABOR COMPARED WITH EXPECTANT MANAGEMENT FOR PRELABOR RUPTURE OF THE MEMBRANES AT TERM: Obstetric and Perinatal Outcome

Umairah Yaqub; Rubina Mushtaq; Mamoona Mushtaq

Authors

Umairah Yaqub Combined Military Hospital Rawalpindi
Rubina Mushtaq Combined Military Hospital Rawalpindi
Mamoona Mushtaq Combined Military Hospital Rawalpindi

Keywords:

Expectant management, Induction of labor, Prelabor rupture of membranes, Prostaglandin

Abstract

Objective: To compare the management outcome of induction of labor with expectant management in patients with term pre labor rupture of membranes (PROM).

Study Design: Randomized controlled trial.

Place and Duration of Study: This study was conducted in the department of Obstetrics & Gynaecology; Combined Military Hospital Rawalpindi from 25^th July 2010 to 25th January 2011.

Methods: A total of 384 patients were selected for this study, which were divided into two groups by lottery method. Patients in group A were induced with tablet prostaglandin E2 and group B patients were managed expectantly for 24 hours. The outcome of mothers and neonates was recorded on a pre-designed proforma.

Results: The mean duration between PROM to onset of active labor in group A was significantly less (8.4 ± 2.3 hours) as compared to group B in which it was (9.6±2.1 hours) (p = 0.000). The mean duration between PROM to delivery in group A was significantly less in group A (17.4 ± 2.0) versus group B (22.2 ± 2.0 hours) (p = 0.000). The spontaneous vaginal delivery (SVD) rate was considerably higher (p=0.056) in group A in which 161 (83.8%) patients delivered by SVD and 31 (16.1%) patients by LSCS. In group B, 146 (76.0%) patients delivered by SVD and 46 (23.9%) patients by LSCS. In group A, 8 (4.1%) patients developed chorioamnionitis and 13 (6.7%) patients in group B (p = 0.262). In group A there were 178 (92.7%) neonates with APGAR score of > 5 at 1 minute in contrast to 173 (90.1%) in group B with (p = 0.363). Similarly in group A at 5 minutes, there were 178 (92.7%) neonates with APGAR score of > 7 and 173 (90.1%) in group B (p = 0.460). There were 9 (4.6%) cases of neonatal sepsis in group A, in comparison with 12 (6.2%) patients in group B (p = 0.501).

Conclusion: The mean duration of labor in induced patients was less as compared to patients with expectant management.

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OBSTETRIC AND PERINATAL OUTCOME IN INDUCTION OF LABOR COMPARED WITH EXPECTANT MANAGEMENT FOR PRELABOR RUPTURE OF THE MEMBRANES AT TERM