Association of Chronic Urticaria with Decreased Vitamin D Levels in Female Patients visiting Tertiary Care Hospital in Pakistan

Sana Waqar Qureshi; Farid ur Rehman; Bilqees Fatima; Shamsa Kanwal; Sibqa Jamil

doi:10.51253/pafmj.v75iSUPPL-2.7394

Authors

Sana Waqar Qureshi Fauji Foundation Hospital, Rawalpindi Pakistan
Farid ur Rehman Fauji Foundation Hospital, Rawalpindi Pakistan
Bilqees Fatima Fauji Foundation Hospital, Rawalpindi Pakistan
Shamsa Kanwal Fauji Foundation Hospital, Rawalpindi Pakistan
Sibqa Jamil Fauji Foundation Hospital, Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-2.7394

Keywords:

Chronic Urtricaria, Urticaria Activity Score, Vitamin D

Abstract

Objective: To evaluate association of chronic urticaria with decreased serum vitamin D levels in female patients.

Study Design: Comparative cross-sectional study.

Place and Duration of Study: Fauji Foundation Hospital, Rawalpindi Pakistan, from Jan 2020 to Jan 2021.

Methodology: Seventy female patients with chronic urticaria (Group-1) and 70 female age matched patients without urticaria (Group-2) were enrolled in the study by nonprobability sampling technique. Both groups were stratified into 3 age based groups: children (0-18 years), young adults (19-40 years) and middle aged (40-60 years). Inclusion criteria comprised of patients of either sex and of age less than 60 years showing urticarial symptoms at least twice a week for more than 6 weeks.

Serum vitamin D level was evaluated by ELISA (enzyme linked immunosorbent assay). A deficiency in vitamin D was defined as serum 25-(OH)D concentrations <30 ng/mL.

Results: Out of 140 patients, 105(75%) had normal vitamin D levels (group 1=48(45.7%) & group-2=57(54.3%)) whereas 35(25%) were deficient; group 1=22(62.8%) & group 2=13(37.2%) (p-value =0.07). In the children group, 13 out of 15(86.6%) were sufficient whereas 2(13%) were deficient (p-value=0.17). In the young adults group, 40 out of 58(68.9%) were sufficient and 18(31%) were deficient (p-value=0.06). In the middle aged group, 52 out of 67(77.6%) were sufficient and 15(22%) were deficient (p-value=0.82).

Conclusion: There is no association of chronic urticaria with decreased serum vitamin D levels.

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