The Spectrum of Oesophagal Varices, Portal Hypertensive Gastropathy and Child Pugh’s Class in Cirrhotic Patients at Tertiary CareHospital

Authors

  • Muhmmad Asif Farooq Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Muhammad Awais Yasin Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Bushra Parveen Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Hala Mansoor CMH Medical College Lahore, Lahore/ National University of Medical Sciences (NUMS) Pakistan
  • Abdul Latif Khattak Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Muhammad Siddique CMH Medical College Lahore, Lahore/ National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i1.6826

Keywords:

Cirrhosis, Child-pugh’s class, Esophageal varices, Portal hypertensive gastropathy

Abstract

Objective: To find the association of Child-Pugh’s Class with oesophagal varices and portal hypertensive gastropathy in cirrhotic patients at CMH Lahore.

Study Design: Cross sectional study

Place and Duration of Study: Department of Gastroenterology and Department of Pathology, Combined Military Hospital Lahore Pakistan, from Feb to May 2021.

Methodology: All patients with cirrhosis of the liver, irrespective of aetiology, who underwent upper gastrointestinal endoscopy, were included in the study. Lab data was retrieved from the Pathology Department to calculate Child Pugh’s score. Endoscopic findings of oesophagal varices and portal gastropathy were recorded and their correlation/association with Child-Pugh’s Class was calculated separately by using Pearson’s coefficient.

Results: A total of 148 patients were included in the study. Male patients were 90(60.8%) and female were 58(39.2%). The age range was 27-85 years, with the mean of patients being 55.93±13.19 years. Association of Child Pugh’s Class with oesophagal varices and portal hypertensive gastropathy revealed that higher grades of oesophagal varices (Grade-lll) and severe portal hypertensive gastropathy were found in Child Pugh’s Class-B (13.51%, 14.18%) and C (15.54%, 16.2%) as compared to Class- A (4.72 %, 1.35%). Child-Pugh’s Class positively correlates with both oesophagal varices and portal hypertensive gastropathy by Pearson’s coefficient r=0.594 and 0.035, respectively; both have significant p values (p <0.05).

Conclusion: Child-Pugh’s Class has a positive correlation with both oesophagal varices and portal hypertensive gastropathy in patients with cirrhosis

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Published

24-02-2023

Issue

Section

Original Articles

How to Cite

1.
Farooq MA, Yasin MA, Parveen B, Mansoor H, Khattak AL, Siddique M. The Spectrum of Oesophagal Varices, Portal Hypertensive Gastropathy and Child Pugh’s Class in Cirrhotic Patients at Tertiary CareHospital. Pak Armed Forces Med J [Internet]. 2023 Feb. 24 [cited 2024 Jul. 13];73(1):169-72. Available from: https://pafmj.org/PAFMJ/article/view/6826