COMPARISON OF LOCAL METHYLCOBALAMINE INJECTION VERSUS LOCAL BUPIVACAINE INJECTION FOR THE TREATMENT OF ACUTE HERPETIC NEURALGIA

Ghazala Yasmin; Naeem Raza; Arfan -Ul- Bari; Farah Yousaf; Summaya Saleem; Najia Ahmed

doi:10.51253/pafmj.v71i6.6464

Authors

Ghazala Yasmin Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Naeem Raza Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Arfan -Ul- Bari Pakistan Naval Ship Shifa Hospital, Karachi Pakistan
Farah Yousaf Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Summaya Saleem Combined Military Hospital Attock/National University of Medical Sciences (NUMS) Pakistan
Najia Ahmed Pakistan Naval Ship Shifa Hospital, Karachi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v71i6.6464

Keywords:

Acute Herpetic Neuralgia, Pain Score, Methylcobalamin, Bupivacaine

Abstract

Objective: To compare the reduction in mean pain score with local Methylcobalamin injection versus local Bupivacaine injection in patients with acute herpetic neuralgia.

Study Design: Quasi experimental study.

Place and Duration of Study: Dermatology Outpatient Department, Pak Emirates Military Hospital, Rawalpindi, from Jun to Dec 2019.

Methodology: Total 100 patients, having pain score more than 3, fulfilling the selection criteria were divided into two groups. Group A was treated with daily subcutaneous injection Bupivacaine, whereas Group B was treated with daily subcutaneous injection Methycobalamin at the site of neuralgia. Patients were followed up for 4 weeks. The pain score was noted. All the data was entered and analyzed on SPSS version 21.

Results: In this study mean age of patients in group A was 43.82 ± 15.76 years and in group B was 44.76 ± 16.92 years. The mean visual analogue pain score at 4th week in the group A patients was 1.14 ± 0.32 and in group B was 1.90 ± 0.97. Statistically significant difference was found in group A (local Bupivacaine) with visual analogue score (VAS) at 4th week (pvalue=0.002).

Conclusion: The local Bupivacaine injection showed significant reduction in mean pain score than local Methylcobalamin injection in patients with acute herpetic neuralgia.