Association between Histopathologic Type of Ovarian Cancer and Serum CA-125 Level

Hina Perveen; Ghulam Haider; Perwasha Kerio; Saima Zahoor; Khalil Mahar; Paras Memon

doi:10.51253/pafmj.v73iSUPPL-1.5410

Authors

Hina Perveen Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi Pakistan
Ghulam Haider Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi Pakistan
Perwasha Kerio Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi Pakistan
Saima Zahoor Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi Pakistan
Khalil Mahar Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi Pakistan
Paras Memon Department of Medicine, Jinnah Postgraduate Medical Centre, Karachi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73iSUPPL-1.5410

Keywords:

Epithelial ovarian cancer, Histological type, Ovarian cancer, Serum CA-125, Serous histology, Tumor stage, Tumor size

Abstract

Objective: to find an association between the serum CA-125 level and the histopathological type of ovarian tumor.

Study Design: Cross-sectional study.

Place and Duration of Study: Medical Oncology, Jinnah postgraduate Medical Center, Karachi Pakistan from Jan 2018 to Dec 2019.

Methodology: This study included 107 patients presenting with epithelial ovarian cancer. In each case, histological type, pathological stage, degree of differentiation and serum CA-125 was evaluated. The association between preoperative CA-125 and histopathological type of tumor were evaluated.

Result: About 107 ovarian cancer patients were included. The mean age in our study was 50.80±10.16 years. Raised CA-125 level was found in most of the patients with serous histology 46(56.1%).

Conclusion: Serum level CA-125 elevated in most patients with serous histology. A statistically non-significant association was found between raise CA-125 levels and histological types of ovarian cancer.