Pre-Emptive Analgesia by Intraperitoneal Instillation of Lignocaine in Laparoscopic Cholecystectomy

Abstract

Objective: To compare the effects of preemptive intraperitoneal instillation of local anesthetic (lignocaine) with conventional
instillation after the removal of gall bladder in elective laparoscopic cholecystectomy.

Study Design: Quasi-experimental study.

Place and Duration of study: General Surgical ward, Combined Military Hospital, Rawalpindi Pakistan, from Jan to Apr 2018.

Methodology: Patients fulfilling the inclusion criteria were randomly assorted into two groups. Group A received
intraperitoneal lignocaine at the conventional timing where was in Group B local anesthetic was instilled preemptively at the
time of insertion of trocar. Post operatively pain was measure on visual analogue scale at 3,6 and 12 hours.

Results: Total of 184 patients were followed up post-operatively. Mean age of patients in Group A was 44.5±13.57 years and in
Group B was 46.2±13.9 years. Mean post-operative pain on visual analogue scale score for Group A was 2.53±0.73 and that for
Group B was 2.0±0.66 with p-value<0.01.
Conclusion: The use of preemptive instillation of local anesthetic intraperitoneal was found better as compared to
conventional timing of instillation in reducing the post-operative pain in elective and uncomplicated cases of laparoscopic
cholecystectomy.