A COMPARATIVE STUDY OF DYSLIPIDAEMIA IN DIABETIC PATIENTS WITH AND WITHOUT NEUROPATHY

Abstract

Objective: To evaluate and compare lipid profile of diabetic neuropathic patients and diabetic patients without neuropathy.

Study Design: Cross-sectional comparative study.

Place and Duration of Study: The study was conducted at Multidisciplinary lab 1, Department of Biochemistry and Molecular biology Army Medical College, Rawalpindi in collaboration with department of Neurology PEMH Rawalpindi, from Feb 2018 to Sep 2018.

Material and Methods: The enrolled subjects were divided in to three groups, group I, n=30 healthy individuals taken as controls, group II composed of 30 diagnosed diabetic patients without neuropathy and group III comprised of 30 diagnosed diabetic patients with neuropathy.

Results: There was significant difference in HDL and LDL values between group I and group II. There was also significant difference in HDL and LDL values of group I and group III. There was no statistically significant difference of lipid profile parameters between group II and group III.

Conclusion: There was significant increase of LDL and decrease of HDL in diabetic patients as compared to normal healthy individuals. There was no statistically significant difference observed between the lipid profile of diabetics with and without neuropathy.