EFFECT OF LEVODOPA ON PERSONALITY DISTURRBANCES AND DYSEXECUTIVE SYMPTOMS IN PATIENTS WITH IDIOPATHIC PARKINSON’S DISEASE

Authors

  • Amara Gul The Islamia University of Bahawalpur, Bahwalpur Pakistan
  • Javed Yousaf The Islamia University of Bahawalpur, Bahwalpur Pakistan

Keywords:

Behavior, Levodopa, Parkinson’s disease

Abstract

Objective:

To assess effects of levodopa (L-dopa) on personality disturbances and dysexecutive symptoms in patients with idiopathic Parkinson’s disease (PD).

Study Design: Prospective test-retest design.

Place and Duration of Study: Bahawal Victoria Hospital and Civil Hospital, Bahawalpur, Pakistan during June 2016 to June 2017.

Material and Methods:

Informants of sixty patients with idiopathic PD rated changes in personality on lowa scale of personality change and dysexecutive symptoms on dysexecutive questionnaire after three months of L-dopa treatment. Informants and clinical psychologist who collected data from informants were both blind to the objective of the study.

Results:

Personality disturbances and dysexecutive functioning (dysexecutive symptoms, inhibition, social regulation) were significantly reduced post L-dopa treatment.

Conclusion:

L-dopa is an effective treatment for bringing positive personality and cognition related changes in patients with idiopathic PD.

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Published

31-12-2018

How to Cite

1.
Gul A, Yousaf J. EFFECT OF LEVODOPA ON PERSONALITY DISTURRBANCES AND DYSEXECUTIVE SYMPTOMS IN PATIENTS WITH IDIOPATHIC PARKINSON’S DISEASE. Pak Armed Forces Med J [Internet]. 2018 Dec. 31 [cited 2024 Dec. 28];68(6):1775-79. Available from: https://pafmj.org/PAFMJ/article/view/2613