FREQUENCY OF VARIOUS DYSLIPIDEMIAS IN PATIENTS OF END STAGE RENAL DISEASE UNDERGOING HEMODIALYSIS

Dylsipidemias in Renal Disease

Abstract

Objective: To determine the frequency of various dyslipidemias in patients of End Stage Renal Disease (ESRD) undergoing hemodialysis at Military Hospital (MH) Rawalpindi and Combined Military Hospital (CMH) Lahore.
Study Design: Cross-sectional study
Place and Duration of Study: Nephrology department, MH Rawalpindi and Nephrology department, CMH Lahore, 25th June 2009 to 24th Dec 2009
Patients and Methods: One hundred and twenty six patients with CKD on maintenance haemodialysis were included by convenience non-probability sampling. Predialysis fasting blood samples were obtained and analyzed for serum total cholesterol, high density lipoproteins (HDL), low density lipoproteins (LDL) and serum triglycerides (TGs).
Results: Out of 126 patients, 83 (65.87%) had dyslipidemias. Of these, 66(52.38%) had raised TGs, 37 (29.37%) had low HDL, 30 (23.80%) had raised cholesterol and 13 (10.31%) had an elevated LDL fraction.
Conclusion: Patients of ESRD on hemodialysis suffer from various forms of dyslipidemias. Hypertriglyceridemia and low HDL were the most commonly observed dyslipidemias which should be treated at the earliest to reduce risk of cardiovascular and cerebrovascular disease.