COMPARISON BETWEEN PAIN RELIEF ACHIEVED BY DICLOFENAC ALONE AND THE COMBINATION OF DICLOFENAC AND HYOSCINE IN THE SHORT-TERM TREATMENT OF URETERIC COLIC

Pain Relief Achieved by Diclofenac

Abstract

Object: This study aims to determine whether the combination of diclofenac and hyoscine gives superior pain relief than diclofenac sodium alone.  
Design: A prospective, non-randomized comparative study.  
Place and Duration of Study: The study was conducted in the Emergency Department of Surgical Unit III at Combined Military Hospital, Rawalpindi from October 31, 2004 to May 01, 2005. 
Patients and Methods: A total of 100 patients were included in the study and distributed between two equal groups.  Assessment of pain relief was done at 30 and 60 minutes after the administration of drugs. The diagnosis of ureteric colic was confirmed using urine analysis, plain radiography and ultrasonography. It was a prospective non-randomized comparative trial without blinding. A quasi-experimental study. 
Results: A significantly (p<0.05) greater number of patients treated with a combination of diclofenac and hyoscine achieved pain relief after 30 minutes as compared to those treated with diclofenac alone.  No significant difference was found between the treatment groups after 60 minutes of drug administration.  
Conclusion: The combination of diclofenac and hyoscine gave a faster pain relief as compared to diclofenac alone in patients of ureteric colic.