Mini-Percutaneous Nephrolithotomy versus Retrograde Intrarenal Surgery for Solitary 1-2 cm Renal Stones: A Quasi-Experimental Comparative Study
DOI:
https://doi.org/10.51253/pafmj.v76iSUPPL-8.14578Keywords:
Hospital Stay; Kidney Calculi; Nephrolithiasis; Percutaneous Nephrolithotomy; Postoperative Pain; Retrograde Intrarenal Surgery; Stone-Free Rate; Treatment Outcome; UreteroscopyAbstract
Objective: To compare the efficacy and safety of Mini-Percutaneous Nephrolithotomy (Mini-PCNL) and Retrograde Intrarenal Surgery (RIRS) for solitary renal stones measuring 1-2 cm.
Study Design: Quasi-experimental study.
Place and Duration of Study: Armed Forces Institute of Urology, Rawalpindi, conducted from Oct 2025 to Jan 2026.
Methodology: A total of 100 patients were enrolled by non-probability consecutive sampling and allocated to Mini-PCNL (n=50) or RIRS (n=50). Eligible patients were adults aged 18-60 years with a solitary 1-2 cm renal stone. Stone-free rate at four weeks, operative time, hospital stay, postoperative pain, and complications were compared between groups.
Results: Mini-PCNL achieved a higher stone-free rate than RIRS (90.0% vs. 74.0%, p=0.037) and had a shorter operative time (68.4 ± 15.2 min vs. 85.7 ± 20.2 min, p<0.001). RIRS was associated with a shorter hospital stay (median 3.35 [IQR 3.00–3.88] days vs. 4.57 [4.01–4.97] days, p<0.001) and lower pain scores on postoperative days 1 and 2 (p<0.001). Overall complication rates were comparable (24.0% vs. 20.0%, p=0.629).
Conclusion: Mini-PCNL provided better stone clearance and shorter operative time, whereas RIRS offered less postoperative pain and shorter hospitalization. Procedure selection should be individualized according to clinical priorities and patient preference
Downloads
Published
License
Copyright (c) 2026 Ajmal Khan Jogezai, Qamar Zia, Ajmal Kakar, Muhammad Tahir, Farhaad Tareen, Naseer Ahmed
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
