ASD Device Size to Patient Weight Ratio and Effect on Immediate Complications After Trans Catheter Closure in Pediatric Patients

Madeeha Ikram; Amjad  Mehmood; Maimoona   Saeed; Aziz Ullah; Hafiz Muhammad  Murtaza

doi:10.51253/pafmj.v76iSUPPL-4.14171

Authors

Madeeha Ikram Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Health Disease/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Amjad Mehmood Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Health Disease/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Maimoona Saeed Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Health Disease/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Aziz Ullah Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Health Disease/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Hafiz Muhammad Murtaza Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Health Disease/National University of Medical Sciences (NUMS), Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v76iSUPPL-4.14171

Keywords:

Atrial Septal Defect, Cardiac Catheterization, Heart Septal Defects, Pediatrics, Postoperative Complications

Abstract

Objective: To determine ASD device size to patient weight ratio and its effect on immediate complications after transcatheter ASD closure in pediatric patients.

Study Design: Analytical cross sectional study

Place and Duration of Study: Department of Pediatric Cardiology, Armed Forces Institute of Cardiology/ National Institute of Health, Rawalpindi, from August 2025 to December 2025.

Methodology: Thirty-eight pediatric patients (aged 1–12 years, 10–25 kg) with suitable ASD anatomy and symptomatic children were enrolled. Patients with > 25 kg, associated cardiac lesions requiring surgery, active infection, bleeding disorders, or contraindications to catheter intervention were excluded. Defect size was assessed by transthoracic echocardiography, and the ASD device size-to- patient weight ratio of patients was calculated. Patients were monitored for 24 hours postprocedure for immediate complications. Based on observed outcomes, patients were stratified according to device size-to- patient weight ratio for comparative analysis.

Results: The ASD device size-to-patient weight ratio demonstrated a significant association with immediate complications. An optimal cut-off value of 1.53 was identified, dividing patients into a lower-risk group (≤1.53; 21(55.3%)) and a higher-risk group (>1.53; 17 (44.7%)). Overall, immediate complications occurred in 21.1% of patients. Complications were observed in 4.8% of patients in the lower-risk group compared with 41.2% in the higher-risk group, highlighting a substantially higher complication rate associated with increased device-to- .....

Conclusion: An increased ASD device size-to- patient weight ratio is associated with a higher frequency of immediate complications following transcatheter ASD closure. Ratios exceeding 1.53 should be considered cautiously and reserved for cases where clinical benefits ...

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Author Biographies

Maimoona Saeed, Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Health Disease/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Aziz Ullah, Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Health Disease/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Hafiz Muhammad Murtaza, Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Health Disease/National University of Medical Sciences (NUMS), Rawalpindi Pakistan

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