CLEIDOCRANIAL DYSPLASIA, NEUROFIBROMATOSIS TYPE-I WITH FRONTAL LOBE GLIOMA

Cleidocranial Dysplasia Neurofibromatosis

Authors

  • Muhammad Nazir Combined Military Hospital Multan
  • Asim Rafiq Combined Military Hospital Multan

Abstract

Introduction

Cleidocranial Dysplasia is a benign hereditary condition, inherited as an autosomal dominant. The disease has considerable variation of expression. Thirty percent of the cases are due to spontaneous mutation [1]. The gene responsible for cleidocranial dysplasia is a transcription factor in gene and is termed CBFA-I.

Neurofibromatosis type-I represents 90% of NF cases. Prevalence is 1 in 4000 persons, 50% are new mutations, 30% are AD inherited. The NF – I gene has been identified and lies on chromosome 17 q 11.2.

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Published

30-09-2005

Issue

Section

Case Reports

How to Cite

1.
Nazir M, Rafiq A. CLEIDOCRANIAL DYSPLASIA, NEUROFIBROMATOSIS TYPE-I WITH FRONTAL LOBE GLIOMA: Cleidocranial Dysplasia Neurofibromatosis. Pak Armed Forces Med J [Internet]. 2005 Sep. 30 [cited 2024 Sep. 1];55(3):261-4. Available from: https://pafmj.org/PAFMJ/article/view/1242