EFFECT OF PASSIVE SMOKING ON THE LEVELS OF PREGNANCY ASSOCIATED PLASMA PROTEIN –A IN NORMAL RATS

Passive Smoking on the Levels of Pregnancy Associated Plasma Protein

Authors

  • Dr Amena Rahim Department of Biochemistry, Army Medical College Rawalpindi
  • Abdul Khaliq Naveed Army Medical College Rawalpindi
  • Maujid Masood Malik Army Medical College Rawalpind
  • Tehmina Qamar Army Medical College Rawalpind

Keywords:

Pregnancy associated plasma protein- A, Cigarette smoke, Sprague-Dawley strain

Abstract

Objectives: To measure the levels of pregnancy associated plasma protein- A (PAPPA-A) in normal rats exposed to cigarette smoke.

Study Design: Experimental interventional study Place and Duration of Study: Army Medical College, Rawalpindi, in collaboration with national institute of health (NIH), Islamabad. Total duration was of 4 weeks. Material and Method: Sixty albino rats of Sprague- Dawley strain weighing 200-250 gm, divided into two groups. Both the groups were kept in identical chambers. One group of 30 rats was further exposed to passive cigarette smoke for 4 weeks.

Results: No increase was observed in the levels of serum PAPP-A of both the groups: Passive smokers and not exposed to passive smoking i .e. P > 0.05. Conclusions: Smoking does not increase the levels of PAPP-A.

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Published

31-03-2010

Issue

Vol. 60 No. 1 (2010): March

Section

Original Articles

How to Cite

1.
Rahim DA, Naveed AK, Malik MM, Qamar T. EFFECT OF PASSIVE SMOKING ON THE LEVELS OF PREGNANCY ASSOCIATED PLASMA PROTEIN –A IN NORMAL RATS: Passive Smoking on the Levels of Pregnancy Associated Plasma Protein. Pak Armed Forces Med J [Internet]. 2010 Mar. 31 [cited 2025 Jan. 3];60(1):13-6. Available from: https://pafmj.org/PAFMJ/article/view/121