VISUAL QUANTIFICATION OF ADENOSINE STRESS INDUCED TC-99M MIBI MYOCARDIAL PERFUSION SPECT IN LEFT BUNDLE BRANCH BLOCK AND IT’S COMPARISON WITH CORONARY ANGIOGRAPHY

Abstract

Objective: To determine the role of visual quantification of Tc-99m MIBI myocardial perfusion SPECT in left
bundle branch block as compared to coronary angiography findings.
Study Design: Prospective randomized controlled trial.
Place and Duration of Study: Department of Nuclear Medicine, Armed Forces Institute of Pathology and Armed
Forces Institute of Cardiology/National Institute of Heart Diseases; Rawalpindi: Pakistan from 1st Sep 2016 to
31st Jan 2017.
Material and Methods: Thirty six patients with complete left bundle branch block and coronary angiography
done within past 4 months were included in our study. Patients were divided in three groups on the basis of
coronary angiographic findings. Six patients (4 males and 2 females) have normal LAD on coronary angiography,
18 (11 males and 7 females) have less than 50% LAD disease and 12 (9 males and 3 females) have more than 50%
LAD lesions. Gated and non-gated pharmacological stress with adenosine myocardial perfusion SPECT was
carried out in 1-day rest-stress protocol.
Results: There was no significant difference in the baseline data among all these three groups. Mean left
ventricular ejection fraction (LVEF) values were lower in moderate LAD Disease group as compared to other two
groups (42 ± 12.4 vs 58 ± 9.2 and 60.6 ± 10.6), left ventricular end diastolic volume (LVEDV) and left ventricular
..............


Conclusions: Visual quantification of myocardial perfusion scan images is not only simple and easy way of
myocardial assessment in LBBB patients but its results are statistically significant when compared with coronary..........