COMPARISON OF SERUM IMMUNOGLOBULIN LEVELS BEFORE AND AFTER ADENOTONSILLECTOMY AND TONSILLECTOMY

Abstract

Objective: To compare the pre and post-operative serum immunoglobulin levels in patients undergoing tonsillectomy and adenotonsillectomy.
Study Design: Quasi-Experimental Study
Place and Duration of the Study: ENT Department, Combined Military Hospital, Rawalpindi from Febuary 2006 to December 2007
Patients and Methods: Study included 50 patients of adenotonsillectomy and tonsillectomy. Two patients were excluded, because they did not report to the hospital for postoperative investigations. Preoperative serum IgG and IgA levels were measured two weeks before surgery and post operative samples were taken two months after the surgery.
Results: Mean age of the patients was 8.8 years, with maximum patients of 12 years of age (35.4%). There were 36 (75%) male and 12 (25%) female patients. Tonsillectomy was done in 30 (62.5%) patients and adenotonsillectomy in 18 (37.5%) patients. Mean age of patient in case of adenotonsillectomy was 7.17 year and for tonsillectomy 9.9 years. There was a significant rise in the post operative serum IgA level (p= 0.02) while it was insignificant in case of IgG (p= 0.44).
Conclusion: Our study shows a significant rise in the post operative serum IgA level (p= 0.02).