FREQUENCY OF NECROTIZING PANCREATITIS IN PATIENTS OF ACUTE PANCREATITIS WITH RAISED CRP

Necrotizing Pancreatitis in Acute Pancreatitis

Abstract

Objective: To determine the frequency of necrotizing pancreatitis in patients of acute pancreatitis with raised C-reactive protein above 150 mg/l.

Study Design: Descriptive study.

Place and Duration of Study: This study was conducted over a period of 9-months (1st November 2010 to 30th July 2011) at surgical department of Combined Military Hospital and Military Hospital, Rawalpindi.

Patients and Methods: Forty three patients from surgical out patient department (OPD) at CMH, MH Rawalpindi fulfilling the inclusion criteria was selected and informed written consent taken. The diagnosis of pancreatitis was made by trainees and consultants clinically and with the aid of raised serum amylase level. After diagnosis serum CRP was measured on admission. CT-scan with IV contrast was carried out on 7^th day of diagnosis and presence of pancreatic necrosis was noted.

Results: Necrotizing pancreatitis was found in 3 out of 43 patients (7%). CRP of all patients of necrotizing pancreatitis was greater than 150mg/l.

Conclusion: A CRP level of greater than 150 mg/l is highly suggestive of acute necrotizing pancreatitis.