Diagnostic Accuracy of Computed Tomography Scan for Solitary Liver Lesions Using Histopathology as the Gold Standard

Qaiser Iqbal; Nausheen  Qaisar; Furrukh  Sher; Saleem  Bangash; Naimat  Ullah; Ejaz  Ahmad

doi:10.51253/pafmj.v75i6.11045

Authors

Qaiser Iqbal Department of Gastroenterology, Pak Emirate Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Nausheen Qaisar Department of Medicine, Pak Emirate Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Furrukh Sher Department of Gastroenterology, Pak Emirate Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Saleem Bangash Department of Gastroenterology, Pak Emirate Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Naimat Ullah Department of Gastroenterology, Pak Emirate Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Ejaz Ahmad Department of Gastroenterology, Pak Emirate Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i6.11045

Keywords:

CT scan, Diagnostic accuracy, Histopathology, and Malignant Liver Lesion

Abstract

Objective: To compare the diagnostic accuracy of CT scan in identifying solitary liver lesions, in reference to histopathology as the gold standard.

Study Design: Cross-sectional Study.

Place and Duration of Study: Department of Gastroenterology, Pak Emirate Military Hospital, Rawalpindi, Pakistan, from Jan to Jun 2023.

Methodology: A total of 180 patients of both genders, aged 30 to 70 years, who were clinically diagnosed of a solitary liver lesion were included. CT was studied for liver lesions, attenuation value was obtained, and diagnosis was then confirmed with aspiration, cytology, and histopathology by a consultant pathologist. Data was recorded on a proforma and analyzed through SPSS.

Results: The Mean age of 51.82±5.98 years. Male patients were 135(75%), and 45(25%) were female patients. CT scan diagnosed 101(56.1%) patients, while histopathology diagnosed 96(53.3%) patients with malignant liver lesions. CT scan has shown sensitivity of 91.6%, specificity 84.5% and diagnostic accuracy of 88%, PPV 87.1% and NPV 89.8% in the diagnosis of malignant liver lesions.

Conclusion: The results of our study showed that a CT scan is a useful tool in diagnosing malignant liver masses and helps to avoid unnecessary liver biopsy.

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