Management of Prosthetic Tricuspid Valve Thrombosis with Streptokinase

Azizullah; Nadeem Sadiq; Muhammad Asad Farhan; Abubakar Sadiq; Sana Imtiaz

doi:10.51253/pafmj.v73iSUPPL-3.10643

Authors

Azizullah Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/ National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Nadeem Sadiq Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/ National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Muhammad Asad Farhan Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/ National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Abubakar Sadiq Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/ National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Sana Imtiaz Department of Paediatric Cardiology, Armed Forces Institute of Cardiology/National Institute of Heart Diseases/ National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73iSUPPL-3.10643

Keywords:

Intravenous streptokinase, Prosthetic valve thrombosis, Valve replacement

Abstract

Despite improvements in the design of mechanical prosthetic heart valves and regular use of anticoagulation, prosthetic heart valve thrombosis remain the most dreadful complication associated with high mortality. Surgical thrombectomy or valvereplacement is used as a conventional therapy. Medical thrombolysis, on the other hand, is a therapy choice. Present case is of a 26-year old female with Ebstein's irregularity who effectively endured tricuspid prosthetic valve thrombolysis usingintravenous Streptokinase (SK). The outcome of our patient supports that SK can be an adequate therapeutic option for thrombolysis of tricuspid Prosthetic Valve Thrombosis (PVT) in children and adolescents.