Frequencies of Various Transfusion Reactions in a Tertiary Care Hospital in Karachi

Madiha  Andleeb; Muhammad Zulqernain  Imran; Noreen  Shakeel; Amna  Qamar; Huma  Tariq

doi:10.51253/pafmj.v76iSUPPL-6.10488

Authors

Madiha Andleeb Department of Hematology, Dr. Ziauddin Medical University & Hospital, Karachi Pakistan
Muhammad Zulqernain Imran Department of Hematology, Dr. Ziauddin Medical University & Hospital, Karachi Pakistan
Noreen Shakeel Department of Hematology, Dr. Ziauddin Medical University & Hospital, Karachi Pakistan
Amna Qamar Department of Hematology, Dr. Ziauddin Medical University & Hospital, Karachi Pakistan
Huma Tariq Department of Hematology, Dr. Ziauddin Medical University & Hospital, Karachi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v76iSUPPL-6.10488

Keywords:

Blood Transfusion/Adverse Effects, Blood Donors Hemovigilance, Patient Safety, Recipients

Abstract

Objective: To determine frequency of various transfusion reactions among transfusion recipients in a tertiary care hospital in Karachi.

Study Design: Cross sectional study.

Place and Duration of Study: Dr. Ziauddin Hospital, North Nazimabad, Karachi Pakistan, from Jan 2019 to Jun 2021.

Methodology: All transfusion reactions reported to the blood bank of Dr. Ziauddin Hospital were noted on the work-up form. Age, gender, type of products transfused, pre and post-transfusion reaction vitals including Blood pressure, Temperature, Pulse, Respiratory rate, time of the start of transfusion, and appearance of symptoms were recorded on proforma. Issue proforma, post-transfusion sample were sought.

Results: 8785 patients were admitted and received blood transfusions. The median age was 30 years. 4628(52.68%) were female and 4157(47.32%) were male. Out of these, 22 patients (0.25%) developed a transfusion reaction, while 8763 patients (99.75%) did not experience any reaction. The most commonly reported sign and symptoms were chills 13(59.09%) and fever 10(45.45%). FNHTR was the most common type of reaction, 9(40.91%), 8(36.36%) were identified as ATRs.

Conclusion: The frequency of transfusion reactions varies significantly in different geographical regions due to differences in hemovigilance systems. This variation may be due to underreporting of transfusion reactions by clinical staff, who may lack knowledge on reporting them properly. To determine the variations in transfusion reaction patterns more accurately, further studies on a larger scale are required.

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