A Case of Co-infection of SARS-CoV-2 and Influenza-B

Faraz Ahmed; Muhammad Ali Rathore; Eijaz Ghani; Saifullah Khan Niazi; Hammad Hussain; Hina Hammad

doi:10.51253/pafmj.v75i2.10232

Authors

Faraz Ahmed Department of Virology, Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Muhammad Ali Rathore Department of Virology, Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Eijaz Ghani Department of Virology, Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Saifullah Khan Niazi Department of Virology, Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Hammad Hussain Department of Virology, Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
Hina Hammad Department of Virology, Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS), Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i2.10232

Keywords:

Co-infection, COVID-19, Influenza

Abstract

The emergence of COVID-19 pandemic has led to significant public health concerns worldwide. As the influenza season coincides with the COVID-19 pandemic, the possibility of co-infection with influenza virus is a significant concern. Co-infection of COVID-19 and influenza could lead to severe respiratory complications and pose a serious threat to public health. Therefore, it is crucial to understand the potential consequences of such co-infections and develop strategies to prevent and manage them.

We present here a case of 51 years old male who reported with high grade fever, cough, body aches and myalgia for 2 days. Blood complete picture revealed leucopenia. Nasopharyngeal swab specimen was taken and respiratory multiplex PCR was performed on 2^nd day of illness. Multiplex PCR result came out to be positive for both COVID-19 and Influenza B, confirming co-infection.

Downloads

Download data is not yet available.

References

Waris A, Atta UK, Ali M, et al. COVID-19 outbreak: current scenario of Pakistan. New Microbes New Infect 2020; 35(100681): 100681. https://doi.org/10.1016/j.nmni.2020.100681

Rasheed R, Rizwan A, Javed H, et al. Socio-economic and environmental impacts of COVID-19 pandemic in Pakistan—an integrated analysis. Environ Sci Pollut Res Int 2021; 28(16): 19926-19943.

https://doi.org/10.1007/s11356-021-13558-6

Dadashi M, Khaleghnejad S, Abedi Elkhichi P, et al. COVID-19 and influenza co-infection: A systematic review and meta-analysis. Front Med 2021; 8: 681469.

https://doi.org/10.3389/fmed.2021.681469

Gardinassi LG, Souza COS, de Lima DV, et al. Transcriptomic approaches in COVID-19: From infection to vaccines. Omics approaches and technologies in COVID-19. Elsevier 2023: 125–144.

Mancini F, Barbanti F, Scaturro M, et al. Multiplex real-time reverse-transcription polymerase chain reaction assays for diagnostic testing of severe acute respiratory syndrome Coronavirus 2 and seasonal influenza viruses. J Infect Dis 2021; 223(5): 765-774. https://doi.org/10.1093/infdis/jiaa711

Lansbury L, Lim B, Baskaran V, et al. Co-infections in people with COVID-19: a systematic review and meta-analysis. J Infect 2020; 81(2): 266-275.

https://doi.org/10.1016/j.jinf.2020.05.046

Konala VM, Adapa S, Naramala S, et al. A Case Series of Patients Coinfected With Influenza and COVID-19. J Investig Med High Impact Case Rep 2020; 8:2324709620934674.

https://doi.org/10.1177/2324709620934674

Ali R, Patel A, Chan KH, et al. A Case Series of SARS-CoV-2 and Influenza Co-infection. Cureus 2021; 13(8): e17597.

https://doi.org/10.7759/cureus.17597

Alosaimi B, Naeem A, Hamed ME, et al. Influenza co-infection associated with severity and mortality in COVID-19 patients. Virol J 2021; 18(1): 127.

https://doi.org/10.1186/s12985-021-01594-0

Ilyicheva TN, Netesov SV, Gureyev VN, et al. COVID-19, Influenza, and Other Acute Respiratory Viral Infections: Etiology, Immunopathogenesis, Diagnosis, and Treatment. Part I. Mol Genet Microbiol Virol 2022; 37(1): 1-9.

https://doi.org/10.3103/S089141682201