Effectiveness of Rapid Sequence Intubation Versus Non-Rapid Sequence Intubation In Traumatic Brain Injury Patients In Emergency Department
DOI:
https://doi.org/10.51253/pafmj.v76iSUPPL-6.10125Keywords:
Intubation, non-RSI, RSI, traumatic brain injury (TBI).Abstract
Objective: To compare the success of intubation and complications associated with performing rapid sequence intubation (RSI) versus non-rapid sequence intubation (NRSI) in patients with traumatic brain injury (TBI) presenting in the emergency department of a tertiary care hospital.
Study Design: Quasi experimental study
Place and Duration of Study: Department of Accident and emergency, Pak-Emirates Military Hospital Rawalpindi, Pakistan from May-Dec 2022
Methodology: The RSI group was intubated as per international RSI protocol with Injection Midazolam 0.1 mg/kg as the sedative agent and Injection Suxamethonium 2 mg/kg as the paralytic agent. Standard Macintosh blade of appropriate size according to patient parameters was used for intubating the trachea. Intubation done by the non-RSI method included intubation by Injection Midazolam 0.1 mg/kg alone without the use of any paralytic agent.
Results: When analyzing the primary outcomes of intubation success between both groups and number of attempts to achieve success, results showed success of intubation at first attempt in 89(84.8%) and on second attempt in 09 (8.6%) patients in the RSI group with an overall success rate in 98(93.3%) and intubation failure in 07(6.7%) patients (p<0.001). In comparison success of intubation in the non-RSI group revealed success at first attempt in 85(81%) patients with 07(6.7%) patients intubated in the second attempt with overall success in 92(87.6%) and failure in 13(12.4%) of the patients (p<0.001).
Conclusion: We conclude that rapid sequence intubation be considered as first-line intubation method for TBI when no contraindication for paralytic agent is present.
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1. Rahman U, Hamid M, Dasti MS, Nouman T, Vedovelli L, Javid A. Traumatic brain injuries: a cross-sectional study of traumatic brain injuries at a tertiary care trauma center in the Punjab, Pakistan. Disaster Med Public Health Prep 2022;17:e89.
https://doi.org/10.1017/dmp.2021.361
2. Yaqoob U, Javeed F, Rehman L, Pahwani M, Madni S, Uddin MM. Emergency Department Outcome of Patients with Traumatic Brain Injury–A Retrospective Study from Pakistan. Pak J Neurol Surg 2021;25(2):237-244.
https://doi.org/10.36552/pjns.v25i2.540
3. Khan M, Yaqoob U, Hassan Z, Uddin MM. Immediate Outcomes of Traumatic Brain Injury at a Tertiary Care Hospital of Pakistan-A Retrospective Study. Res Square;2021. https://doi.org/10.21203/rs.3.rs-84330/v2
4. Dikmen S, Machamer J, Manley GT, Yuh EL, Nelson LD, Temkin NR, et al. Functional status examination versus glasgow outcome scale extended as outcome measures in traumatic brain injuries: how do they compare? J Neurotrauma 2019;36(16):2423-2429. https://doi.org/10.1089/neu.2018.6198
5. Ganti L, Stead T, Daneshvar Y, Bodhit AN, Pulvino C, Ayala SW, et al. GCS 15: when mild TBI isn’t so mild. Neurol Res Pract 2019;1(1):1-8. https://doi.org/10.1186/s42466-018-0001-1
6. Nik A, Andalibi MSS, Ehsaei MR, Zarifian A, Karimiani EG, Bahadoorkhan G. The efficacy of glasgow coma scale (GCS) score and acute physiology and chronic health evaluation (APACHE) II for predicting hospital mortality of ICU patients with acute traumatic brain injury. Bull Emerg Trauma 2018;6(2):141.https://doi.org/10.29252/beat-060208
7. Kramer N, Lebowitz D, Walsh M, Ganti L. Rapid sequence intubation in traumatic brain-injured adults. Cureus 2018;10(4):e2530. https://doi.org/10.7759/cureus.2530
8. Klucka J, Kosinova M, Zacharowski K, De Hert S, Kratochvil M, Toukalkova M, et al. Rapid sequence induction: an international survey. European J Anaesthesiol 2020;37(6):435. https://doi.org/10.1097/eja.0000000000001194
9. Wahlen BM, El-Menyar A, Asim M, Al-Thani H. Rapid sequence induction (RSI) in trauma patients: Insights from healthcare providers. World J Emerg Med 2019;10(1):19. https://doi.org/10.5847/wjem.j.1920-8642.2019.01.003
10. Dao AQ, Mohapatra S, Kuza C, Moon TS. Traumatic brain injury and RSI is rocuronium or succinylcholine preferred? Curr Opin Anaesthesiol 2023;36(2):163-167.
https://doi.org/10.1097/aco.0000000000001225
11. Gravesteijn BY, Sewalt CA, Nieboer D, Menon DK, Maas A, Lecky F, et al. Tracheal intubation in traumatic brain injury: a multicentre prospective observational study. Br J Anaesth 2020;125(4):505-517. https://doi.org/10.1016/j.bja.2020.05.067
12. Botha JC, Lourens A, Stassen W. Rapid sequence intubation: a survey of current practice in the South African pre-hospital setting. Int J Emerg Med 2021;14(1):1-11. https://doi.org/10.1186/s12245-021-00368-3
13. Delorenzo A, St Clair T, Andrew E, Bernard S, Smith K. Prehospital rapid sequence intubation by intensive care flight paramedics. Prehosp Emerg Care 2018;22(5):595-601. https://doi.org/10.1080/10903127.2018.1426666
14. Muñoz ÁM, Estrada M, Quintero JA, Umaña M. Rapid Intubation Sequence: 4-Year Experience in an Emergency Department. Open Access Emerg Med 2021; 13:449-455. https://doi.org/10.2147/oaem.s321365
15. Goto Y, Goto T, Okamoto H, Hagiwara Y, Watase H, Hasegawa K, et al. Factors associated with successful rescue intubation attempts in the emergency department: an analysis of multicenter prospective observational study in Japan. Acute Med Surg 2020;7(1):e462.https://doi.org/10.1002/ams2.462
16. Nausheen F, Niknafs NP, MacLean DJ, Olvera DJ, Wolfe AC, Pennington TW, et al. The HEAVEN criteria predict laryngoscopic view and intubation success for both direct and video laryngoscopy: a cohort analysis. Scand J Trauma Resusc Emerg Med 2019;27(1):1-9.
https://doi.org/10.1186/s13049-019-0614-6
17. Zeuchner J, Graf J, Elander L, Frisk J, Fredrikson M, Chew MS. Introduction of a rapid sequence induction checklist and its effect on compliance to guidelines and complications. Acta Anaesthesiol Scand 2021;65(9):1205-1212.
https://doi.org/10.1111/aas.13947
18. Bhatia PK, Mohammed S. Aspiration Pneumonia after Rapid Sequence Intubation: A Diagnostic Dilemma! Indian J Crit Care Med 2021;25(2):111-112.
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Copyright (c) 2026 Syed Muhammad Hassan Kazmi, Muhammad Moaz Tamur Sarwar, Asma Bibi, Syeda Zainab, Zia Ul Haq, Muhammad Azeem

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