Comparison of Different Treatment Strategies Combating COVID-19 in Pakistan

  • Afsheen Mansoor Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad Pakistan
  • Muhammad Talal khan Bakhtawar Amin Medical and Dental College, Multan Pakistan
  • Aleena Hussain Islamabad Medical and Dental College, Islamabad Pakistan
  • Emaan Mansoor Islamic International Dental College, Islamabad Pakistan
  • Ambreen Gul Dental College, HITEC Institute of Medical Sciences, Taxila /National University of Medical Sciences (NUMS) Pakistan
  • Anber Saleem Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad Pakistan
Keywords: Azithromycin, Chloroquine, COVID-19, Doxycycline, Ivermectin, Lopinavir


Objective: To compare different treatment strategies for patients of COVID-19 in Pakistan.

Study Design: Retrospective longitudinal study.

Place and Duration of Study: Abbas Medical Hospital, Muzaffarabad Pakistan, during Apr 2021.

Methodology: One hundred and twenty, COVID-19-positive patients between 31-45 years of age were admitted to Abbas hospital after carrying out the rRT-PCR test. Group-A was administered Azithromycin, while Group-B was treated with Azithromycin in combination with Hydroxychloroquine. Group-C was given a combination of oral Ivermectin and Doxycycline, and Group-D was treated with Lopinavir. Diagnostic tests include rRT-PCR, blood parameters such as creatinine,random blood sugar, alanine aminotransferase, complete blood count, ECG, chest x-ray and blood biomarkers including procalcitonin, C-reactive protein, lactate dehydrogenase and ferritin were performed at Day 1, 5, 7, 14 and 30.

Results: Patients treated with Azithromycin revealed the highest recovery of about (77.80%) among COVID-19 patients,followed by the combination of Azithromycin and Hydroxychloroquine which was (65.56%), the combination of Ivermectin and Doxycycline was (19.63%), and Lopinavir was (9.06%) displayed minimum potency in recovering the COVID-19 positive patients (p-value <0.001).

Conclusions: Azithromycin was most effective in helping patients recover from COVID-19, followed by a combination of azithromycin and Hydroxychloroquine. Patients who recovered after treatment with Ivermectin Doxycycline were lower,followed by those who recovered with Lopinavir only.


Download data is not yet available.
How to Cite
Mansoor, A., khan, M., Hussain, A., Mansoor, E., Gul, A., & Saleem, A. (2022). Comparison of Different Treatment Strategies Combating COVID-19 in Pakistan. Pakistan Armed Forces Medical Journal, 72(5), 1752-56.
Original Articles