Histopathological Analysis of Gastric Biopsies using Updated Sydney System

  • Muhammad Zubair Najran Armed Forces Hospital, Saudi Arabia
  • Nabeel Khan Afridi Najran Armed Forces Hospital, Saudi Arabia
  • Muhammad Amir Nawaid Najran Armed Forces Hospital, Saudi Arabia
  • Hassan Tariq Armed Forces Institute of Pathology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Akhter Ali Bajwa Combined Military Hospital, Thall/National University of Medical Sciences (NUMS) Pakistan
  • Naveed Khan Combined Military Hospital, Peshawar/National University of Medical Sciences (NUMS) Pakistan
Keywords: Gastritis, Helicobacter Pylori, Non-ulcer dyspepsia

Abstract

Objective: To analyse histopathological findings in gastric biopsies of patients with dyspepsia using an updated Sydney System.

Study Design: Retrospective longitudinal study.

Place and Duration of Study: Histopathology Department, Najran Armed Forces Hospital (NAFH), Saudi Arabia, from Jan 2013 to Mar 2020.

Methodology: A total of 408 cases whose gastric biopsies were included in the study, and their histological features were studied.

Results: Among 408 patients included in the study, 191(46.8%) were males, and 217(53.2%) were females. The mean age was 37.0±15.0 years. A total of 343 patients showed gastritis, which was mild 152(44.3%), moderate 158(46.1%) and severe 33(9.6%), respectively. The activity was observed in 200(49.0%) patients. H.pylori infection was observed in 196(48.0%) patients and intestinal metaplasia in 9(2.2%) patients.

Conclusion: Most of the cases with dyspepsia showed histological evidence of gastritis. However, a significant number of patients had no gastric mucosal abnormality. Therefore, adequate and timely treatment of H.pylori infection can significantly reduce related morbidity.

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Author Biography

Nabeel Khan Afridi, Najran Armed Forces Hospital, Saudi Arabia

Classified Hematologist

Published
2022-12-29
How to Cite
Zubair, M., Afridi, N., Nawaid, M., Tariq, H., Bajwa, A., & Khan, N. (2022). Histopathological Analysis of Gastric Biopsies using Updated Sydney System. Pakistan Armed Forces Medical Journal, 72(6), 1969-72. https://doi.org/10.51253/pafmj.v72i6.6458
Section
Original Articles

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