HISTOLOGICAL CONSEQUENCES OF CONSUMPTION OF ENERGY DRINK ON RENAL TUBULES

Energy Drink and Renal Tubules

  • Ammara Rasheed Nishtar Medical University, Multan Pakistan
  • Imtiaz Aslam Fatima Jinnah Medical University, Lahore Pakistan
  • Raafea Tafweez King Edward Medical University, Lahore Pakistan
  • Muhammad Rizwan Bashir Kiani Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Kamran Ameer Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Arslan Akbar Saeed Nishtar Medical University, Multan Pakistan
Keywords: Caffeine, Energy drink, Renal tubules, Renal vacuolization, Taurine

Abstract

Objective: To investigate the outcomes of energy drink on renal tubules of albino rats.

Study Design: Laboratory-based experimental study.

Place and Duration of Study: King Edward Medical University, Lahore from Aug 2018 to Dec 2019.

Methodology: Group A and B were experimental groups received 1.5ml/kg and 2.2ml/kg body weight of energy drink, respectively. Group C received 1ml/kg body weight of distilled water. Comparison among groups was made by applying One-Way ANOVA for quantitative variables. Tukey’ test was used for post hoc analysis. For qualitative variables, chi-square test was applied to make comparison among groups

Results: The mean initial and final weight of animals was around 152.7 ± 5.3g and 171.9 ± 5.1g, respectively. The mean paired kidney weight, relative tissue weight index, length and width of kidneys for all three groups were found insignificant. Microscopic examination showed tubular vacuolization in groups A and B showing p-value of 0.027.

Conclusion: Consumption of energy drinks results in histopathological injury of epithelial cells of renal tubules.

Downloads

Download data is not yet available.
Published
2021-10-31
How to Cite
Rasheed, A., Aslam, I., Tafweez, R., Bashir Kiani, M. R., Ameer, M., & Saeed, A. (2021). HISTOLOGICAL CONSEQUENCES OF CONSUMPTION OF ENERGY DRINK ON RENAL TUBULES. PAFMJ, 71(5), 1736-40. https://doi.org/10.51253/pafmj.v71i5.6326
Section
Original Articles