SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY

  • Asif Aziz Jinnah Postgraduate Medical Center, Karachi Pakistan
  • Sarwat Ashraf Jinnah Postgraduate Medical Center, Karachi Pakistan
  • Mir Tahir Hussain Talpur Jinnah Postgraduate Medical Center, Karachi Pakistan
  • Nasrullah Aamer People's University of Medical and Health Sciences , Nawabshah Pakistan
  • Sagheer Ahmed Solangi Jinnah Postgraduate Medical Center, Karachi Pakistan
  • Khalil Ullah Shabir Jinnah Postgraduate Medical Center, Karachi Pakistan
  • Moiz Ahmed Jinnah Postgraduate Medical Center, Karachi Pakistan
  • Kiran Abbas Jinnah Postgraduate Medical Center, Karachi Pakistan
Keywords: Ascites, Cirrhosis, Spontaneous bacterial peritonitis

Abstract

Objective: To determine the frequency of spontaneous bacterial peritonitis in asymptomatic cirrhotic patients with ascites.

Study Design: Cross-sectional study.

Place and Duration of Study: Medical outpatient department, Medical unit III, Ward-7, JPMC, Karachi, from Feb 2018 to Aug 2018.

Methodology: All patients between the age of 18 to 60 years and presenting with confirmed ascites due to liver cirrhosis were included. Those with ascites due to other causes were excluded from the study. After obtaining consent, diagnostic ascitic paracentesis was done and sent to the laboratory for evaluation.

Results: A total of 130 patients were enrolled in the study. The mean age of ascites patients was 46.94 ± 7.67 years. There were 73 (56.2%) male while 57 (43.8%) were female. Spontaneous bacterial peritonitis was detected among 38 (29.2%) patients. Among these, 15 patients (11.5%) had positive culture of spontaneous bacterial peritonitis and detected organisms like E.coli (5.4%), Klebsiella (3.1%), Pneumococcus (2.3%) & Streptococcus viridians (0.8%). Frequency of spontaneous bacterial peritonitis increased with increasing age. Male gender was more affected of spontaneous bacterial peritonitis. Lower the weight increasing duration of ascites were associated with higher incidence of spontaneous bacterial peritonitis (p-value = 0.001 and 0.311 respectively).

Conclusion: Spontaneous bacterial peritonitis was detected among one-third of the patients suffering from cirrhosis, making it a grave complication that requires prompt treatment.

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Published
2020-10-30
How to Cite
Aziz, A., Ashraf, S., Talpur, M. T., Aamer, N., Solangi, S., Shabir, K., Ahmed, M., & Abbas, K. (2020). SPONTANEOUS BACTERIAL PERITONITIS IN ASYMPTOMATIC CIRRHOTIC PATIENTS WITH ASCITES IN A TERTIARY CARE HOSPITAL: A CROSS-SECTIONAL STUDY. Pakistan Armed Forces Medical Journal, 70(5), 1408-12. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/5574
Section
Original Articles