EVALUATION OF PERIPAPILLARY RETINAL NERVE FIBRE LAYER AND CENTRAL MACULAR THICKNESS INADULTS WITH HYPEROPIC ANISOMETROPIC AMBLYOPIA

  • Tanveer Ahmed Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Khizar Niazi Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Sobia Usman Shah Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Junaid Afsar Khan Combined Military Hospital Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Husnain Muhammad Bukhsh Ganga Ram Hospital, Lahore Pakistan
  • Muhammad Arslan Ashraf Mayo Hospital, Lahore Pakistan
Keywords: Anisometropia, Amblyopia, Central macular thickness (CMT), Optical coherence tomography (OCT), Peri-papillary retinal nerve fibre layer (pRNFL)

Abstract

Objective: To study per-papillary retinal nerve fibre layer (pRNFL) and central macular thickness (CMT) changes
in adults with hyperopic anisometropic amblyopia using optical coherence tomography.

Study Design: Cross sectional study.

Place and Duration of Study: Combined Military Hospital, Lahore, Pakistan, from Oct 2019 to Feb 2020.

Methodology: In this study 30 adults, 18-40 years of age were included who presented in our clinic with monocular poor vision. They underwent detailed ophthalmic clinical examination: including corrected and uncorrected distance visual acuity, slit lamp bio-microscopy and fundus examination with 90 diopter lens. After fulfilling criteria of anisometropic amblyopia, central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness was measured by using RS-3000 SLO, NIDEK Co, Japan spectral domain optical coherence tomography device and compared the central maular thickness (CMT) and per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic and fellow eye of same individual.

Results: The mean change in per-papillary retinal nerve fibre layer (pRNFL) thickness in amblyopic eyes, 121.48
± 4.90 μm and non amblyopic eyes was 112.92 ± 4.72 μm with statistical significance (p<0.001). The mean change in central macular thickness (CMT) in amblyopic eyes was 198.50 ± 5.30 μm and non amblyopic eyes was 206.80 ± 3.11 μm with statistical significance (p<0.001). There was significant increase in per-papillary retinal nerve fibre layer (pRNFL) thickness and significant decrease in central macular thickness (CMT) on comparing the amblyopic and the fellow eyes of the same patients.

Conclusion: Central macular thickness (CMT) decreased.........................

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Published
2021-02-24
How to Cite
Ahmed, T., Niazi, K., Shah, S., Khan, J., Bukhsh, H., & Ashraf, M. (2021). EVALUATION OF PERIPAPILLARY RETINAL NERVE FIBRE LAYER AND CENTRAL MACULAR THICKNESS INADULTS WITH HYPEROPIC ANISOMETROPIC AMBLYOPIA. PAFMJ, 71(1), 162-66. https://doi.org/10.51253/pafmj.v71i1.3975
Section
Original Articles