INHIBITION OF SURGICALLY INDUCED MIOSIS WITH NEPAFENAC

  • Rabbia Mirza Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Imran Basit Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Summaya Khan Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Zahid Ullah Combined Military Hospital Bannu/ National University of Medical Sciences (NUMS) Pakistan
  • Shahid Tarar Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Awais Armed Forces Institute of Ophthalmology/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Keywords: Nepafenac, miosis, transoperative mydriasis, prophylactic, cataract surgery

Abstract

Objective: To assess the efficacy of prophylactic administration of 0.1% nepafenac in the maintenance of trans-operative mydriasis following cataract surgery.

Study Design: Quasi-experimental study.

Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from Oct 2018 to Mar 2019.

Methodology: A total of 70 patients undergoing cataract surgery phacoemulsification were randomly placed in either the control group or the nepafenac group. Nepafenac eye drops were administered as one drop 8 hourly, 3 days before surgery. Control group didn’t receive any medication preoperatively Mydriasis was measured trans-operatively before surgery, after aspiration of the cortex, and then at the end of surgery. Patients of both groups received tobradex 2 weeks post-surgery.

Results: Post-surgery statistically significant (0.001) difference was observed in the mean pupil size between the nepafenac group (7.88 ± 0.49) and the control group (6.57 ± 0.92 mm).

Conclusion: Use of nepafenac prophylactically was very effective in maintenance of trans-operative mydriasis in cataract surgery.

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Published
2021-08-27
How to Cite
Mirza, R., Basit, I., Khan, S., Ullah, Z., Tarar, S., & Awais, M. (2021). INHIBITION OF SURGICALLY INDUCED MIOSIS WITH NEPAFENAC. PAFMJ, 71(4), 1451-54. https://doi.org/10.51253/pafmj.v71i3.3324
Section
Original Articles

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