Comparison of Total Intravenous Anesthesia (TIVA) Versus Spinal Anesthesia in Total Knee Arthroplasty (TKA)

Authors

  • Mirza Hamid Beg Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Khalid Buland Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Muhammad Huzaifa Sharif Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Shahzada Irfan Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Taimur Azam Khan Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Osama Abdul Mateen Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v76iSUPPL-3.9593

Keywords:

Postoperative pain; Propofol ; Spinal anesthesia; Total knee arthroplasty

Abstract

Objective: To assess outcomes of two anesthesia techniques utilized in total knee arthroplasty (TKA): total intravenous anesthesia (TIVA) and spinal anesthesia.

Study Design: Prospective Comparative Study.

Place and Duration of Study: Orthopedics Department, Combined Military Hospital, Rawalpindi, Pakistan, from May to Nov 22.

Methodology: A total of 78 patients, aged <75 years and with end-stage osteoarthritis, underwent TKA by either TIVA or spinal anesthesia. Individuals with medical comorbidities were excluded. Spinal anesthesia was provided by means of 0.5% bupivacaine, whereas TIVA was administered by using Propofol plus Remifentanil. A visual analogue scale (VAS) was applied to assess postoperative pain. Postoperative complications, e.g., nausea, vomiting, dizziness, postural drop, and deep venous thrombosis (DVT) were monitored for both groups. SPSS-23.0 was used to conduct statistical analysis, while a p-value<0.05 was considered significant.

Results: Thirty-eight patients (48.7%) underwent TIVA, while the remaining 40 cases (51.3%) were treated with spinal anesthesia. The mean age of the former group was 67.4±4.3 years and 66.5±4.7 years for spinal anesthesia. TIVA was capable of significantly lowering the incidence of postoperative pain (p=0.023). The median VAS was 5.0 (IQR: 2.0) for the TIVA and 6.0 (IQR: 2.0) for the spinal anesthesia group. A higher incidence of postoperative dizziness was reported during recovery from spinal anesthesia (n=22; 52%) as compared to TIVA (n=13; 34.2%). No significant difference was observed in terms of nausea/vomiting, postural drop, or DVT during patient recovery. Additionally, hospital stay also remained uniform in both groups.

Conclusion: TIVA is a potentially suitable candidate for the ..

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References

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Published

30-04-2026

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Original Articles

How to Cite

1.
Beg MH, Buland K, Sharif MH, Irfan S, Khan TA, Mateen OA. Comparison of Total Intravenous Anesthesia (TIVA) Versus Spinal Anesthesia in Total Knee Arthroplasty (TKA). Pak Armed Forces Med J [Internet]. 2026 Apr. 30 [cited 2026 May 22];76(SUPPL-3):S488-S492. Available from: https://pafmj.org/PAFMJ/article/view/9593