Patterns, Effects and Outcomes of High Altitude on Skin Diseases in Gilgit Baltistan, Pakistan
DOI:
https://doi.org/10.51253/pafmj.v76iSUPPL-3.6579Keywords:
Eczema, Gilgit Baltistan, High altitude, Pigmentation disorders, Skin diseaseAbstract
Objectives: To determine the effects and outcomes of high altitude on dermatological diseases in patients from Gilgit Baltistan, Pakistan, presenting to a secondary care hospital in Gilgit.
Study Design: Descriptive cross-sectional study.
Place and Duration of Study: Department of Dermatology, Combined Military Hospital (CMH), Gilgit Baltistan, Pakistan, from Mar 2015 to Mar 2017.
Methodology: A total of 4612 patients attending the dermatology OPD from March 2015 to February 2017 were included. Non-residents of Gilgit Baltistan were excluded. Patients were examined by a consultant dermatologist. Diagnoses were primarily clinical, supported where required by skin biopsies, histopathology, laboratory tests, and skin scrapings. Data was analyzed using Statistical Package for the Social Sciences (SPSS) version 11.00 and comparisons were made with other studies.
Results: Of 4612 patients, 2738 (59.40%) were female and 1874 (40.60%) were male (Female: Male ratio of 1.5:1). Eczemas were most common (22.80%), followed by pigmentary disorders (18.60%). Noninfectious diseases (71.00%) predominated over infectious diseases (29.00%). Seasonal variation was evident, with more patients attending in summer (60.40%) than in winter (39.60%).
Conclusion: High-altitude climate significantly influences dermatological disease patterns. Findings can help guide health advisories, preventive strategies, and resource allocation. Photo protection and effective moisturization are important preventive measures.
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References
1. Burki SJ. Historical Dictionary of Pakistan. 4th ed. Lanham (MD): Rowman and Littlefield; 2015.
2. Beall CM. Human evolution at high altitude. In: High altitude medicine and physiology. 5th ed. Boca Raton (FL): CRC Press; 2014. p. 357–377.
3. Burton JL, Savin JA, Champion RH. Introduction, epidemiology and historical bibliography. In: Champion RH, Burton JL, Ebling FJG, editors. Textbook of Dermatology. 5th ed. Oxford: Blackwell Scientific Publications; 1992. p. 1–15.
4. Singh GK, Chatterjee M, Grewal RS, Verma R. Incidence and care of environmental dermatoses in the high‑altitude region of Ladakh, India. Indian J Dermatol 2013; 58: 107–109.
https://doi.org/10.4103/0019-5154.108019
5. Ahmad S, Mahmood N, Ullah S, Suqrat H, Sajid N. The frequency of various skin diseases in patients visiting the OPD of dermatology department at a tertiary care hospital, Aziz Fatima Medical and Dental College, Faisalabad. J Pak Assoc Dermatol 2020; 30: 618–622.
6. Aman S, Nadeem M, Mahmood K, Ghafoor MB. Pattern of skin diseases among patients attending a tertiary care hospital in Lahore, Pakistan. J Taibah Univ Med Sci 2017; 12: 392–396.
https://doi.org/10.1016/j.jtumed.2017.01.011
7. Alam MN, Husain A, Quarashi SA. The pattern of skin and venereal disorders among patients attending the OPD of dermatology and venereology department of a tertiary care private hospital, Dhaka, Bangladesh. J Pak Assoc Dermatol 2017; 27 :10–14.
8. Najdawi F, Fa’ouri M. Frequency and types of skin disorders and associated diabetes mellitus in elderly Jordanians. East Mediterr Health J 2002; 8: 574–578.
9. Al Shobaili HA. The pattern of skin diseases in the Qassim region of Saudi Arabia: what the primary care physician should know. Ann Saudi Med 2010; 30: 448–453.
https://doi.org/10.4103/0256-4947.69936
10. Dimri D, Reddy BV, Kumar Singh A. Profiles of skin diseases in unreached hilly areas of North India. Dermatol Res Pract 2016; 2016: 4573751.
https://doi.org/10.1155/2016/4573751
11. Kaffenberger BH, Shetlar DJ, Norton SA, Rosenbach M. The effect of climate change on skin disease in North America. J Am Acad Dermatol 2017; 76: 140–147.
https://doi.org/10.1016/j.jaad.2016.07.039
12. Fasih S, Arif AB, Younas S. Pattern of skin diseases in Abbas Institute of Medical Sciences, Muzaffarabad. Pak J Physiol 2017; 13: 26–29.
13. Young AR, Claveau J, Rossi AB. Ultraviolet radiation and the skin: photobiology and sunscreen photoprotection. J Am Acad Dermatol 2017; 76(3 Suppl 1): S100–S109.
https://doi.org/10.1016/j.jaad.2016.09.035
14. Wang SQ, Lim HW, editors. Principles and practice of photoprotection. Springer; 2016.
https://doi.org/10.1007/978-1-4939-2399-1
15. Sondenheimer K, Krutmann J. Novel means for photoprotection. Front Med 2018; 5: 162.
https://doi.org/10.3389/fmed.2018.00162
16. Singh A, Kukreti A, Bedi GK, Mahajan VK. Spectrum of high‑altitude dermatoses: experience from the Himalayas. Indian J Dermatol Venereol Leprol 2019; 85: 142–149.
https://doi.org/10.4103/ijdvl.IJDVL_588_17
17. Lee SC, Thomas A, O’Brien C. Effects of hypobaric hypoxia on cutaneous vasodilatation during heat stress at simulated high altitude. Am J Physiol Regul Integr Comp Physiol 2015; 309: R556–R562.
https://doi.org/10.1152/ajpregu.00136.2015
18. Lana JT, Mallipudi A, Ortiz EJ, et al. Risk factors for cutaneous leishmaniasis in a high‑altitude forest region of Peru. Trop Med Health 2021; 49: 40.
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