DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES

Authors

  • Tayyaba Khan Pakistan Institute of Medical Sciences Islamabad Pakistan
  • Tahmina Yousaf Federal General Hospital, Islamabad Pakistan
  • Saera Afghan Pakistan Institute of Medical Sciences Islamabad Pakistan
  • Komail Malik Pakistan Institute of Medical Sciences Islamabad Pakistan

Keywords:

Doppler Ultrasonography, Preeclampsia

Abstract

Objective: To determine the diagnostic accuracy of Doppler ultrasonography during second trimester of pregnancy, to predict pre-eclampsia (PE) in primigravidas.

Study Design: Cross sectional study.

Place and Duration of Study: MCH unit-II, Pakistan Institute of Medical Sciences Islamabad, from Apr 2015 to Oct 2015.

Material and Method: A total of 170 females were recruited for the study. Doppler ultrasound examination of the uterine artery (UA) was performed, using a color Doppler system. Doppler parameters including resistance index (RI) was calculated by the software supplied within the Doppler equipment. Females were labeled as positive if RI >0.7 and were labeled as negative if RI <0.7. Then females were followed till third trimester and were carefully monitored for pre-eclampsia. The data was entered on the pre-designed proforma. Collected data was entered and analyzed through SPSS version 16. A 2x2 table was generated to calculate sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy of Doppler ultrasonography, taking development of PE as gold standard.

Results: The mean age of females was 27.46  4.67 years. The mean gestational age at time of recruitment was 20.95 ± 0.83 weeks. The mean height, weight and BMI of females were 1.66 ± 0.07meters, 72.85 ± 10.61kg and 26.63 ± 4.04kg/m2, respectively. There were 46 (27%) females who were obese while 124 (73%) females had normal BMI. At time of presentation of females, the RI on Doppler USG was >0.7 in 82 (48.2%) females while it was <0.7 in 88 (51.8%) females. There were 82 (48.2%) females who developed PE while 88 (51.8%) females did not develop PE at 20th week of gestation. Thus the calculated sensitivity, specificity, PPV and NPV of RI on Doppler USG were 85.4%, 86.4%, 85.4% and 86.4%. The overall diagnostic accuracy of RI was 85.9%.

Conclusion: Doppler USG is accurate enough that in future we can rely on this tool for prediction of PE in primigravidas.

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Published

25-06-2019

Issue

Section

Original Articles

How to Cite

1.
Khan T, Yousaf T, Afghan S, Malik K. DIAGNOSTIC ACCURACY OF UTERINE ARTERY DOPPLER ULTRASOUND TO PREDICT PREECLAMPSIA IN PRIMIPAROUS FEMALES. Pak Armed Forces Med J [Internet]. 2019 Jun. 25 [cited 2024 Nov. 28];69(3):566-70. Available from: https://pafmj.org/PAFMJ/article/view/3028