Navigating Trial of Labor after Cesarean Section: Insight into Unfavorable Results

Authors

  • Umairah yaqub Department of Gynecology and Obstetrics, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Ayesha Imran Department of Gynecology and Obstetrics, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Viqar Ashraf Department of Gynecology and Obstetrics, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Asifa Siraj Department of Gynecology and Obstetrics, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Qurat ul Ain Aslam Department of Gynecology and Obstetrics, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan
  • Mahpara Tariq Department of Gynecology and Obstetrics, Pak Emirates Military Hospital/National University of Medical Sciences (NUMS), Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v76i1.12841

Keywords:

Bishop Score, Cesarean Section, Hemorrhage, Laparotomy, Trial of Labor After Cesarean Section (TOLAC), Uterine Rupture

Abstract

Objective: To measure the frequency of unfavorable maternal and fetal outcomes in patients who have failed trial of labor after cesarean section (TOLAC) and to compare them to demographic factors and clinical parameters to establish significance. 

Study Design: Quasi-experimental study.

Place and Duration of Study: Department of Gynecology and Obstetrics, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Feb to Dec 2024.

Methodology: After ethical approval, we presented our experience regarding unfavorable outcomes of trial of labor after cesarean section (TOLAC) with demographic characteristics and clinical parameters in Pakistani population. The aim of the study was to help obstetricians to identify the negative indicators of TOLAC to minimize maternal morbidity and improve the success rate. 

Results: The frequency of unfavorable maternal and fetal outcomes was higher in Group B patients. The frequency of peri-partum Hemorrhage was 7(14.3%) in Group A patients and 8(38.1%) in Group B patients, frequency of chorioamnionitis was 2(4.1%) in Group A patients versus 5(23.8%) in Group B patients and the frequency of uterine rupture was 1(4.8%) in Group B patients and none in Group A patient.

Conclusion: We concluded that unfavorable maternal and fetal outcomes of trial of labor after cesarean section are linked to maternal demographics (weight, patient enthusiasm, booking status) and clinical parameters (Bishop score, cervical dilatation, and effacement) at time of admission and they were found more frequently in patients with failed TOLAC.

Downloads

Download data is not yet available.

References

1. Einerson BD, Comstock J, Silver RM, Branch DW, Woodward PJ, Kennedy A. Placenta accreta spectrum disorder: uterine dehiscence, not placental invasion. Obstet Gynecol 2020; 135(5): 1104-1111.

https://doi.org/10.1097/AOG.0000000000003793

2. Kallianidis AF, Maraschini A, Danis J, Colmorn LB, Deneux‐Tharaux C, Donati S, et al. Epidemiological analysis of peripartum hysterectomy across nine European countries. Acta Obstet Gynecol Scand 2020; 99(10): 1364-1373.

https://doi.org/10.1111/aogs.13892

3. Beyene MG, Zemedu TG, Gebregiorgis AH, Ruano AL, Bailey PE. Cesarean delivery rates, hospital readiness and quality of clinical management in Ethiopia: national results from two cross-sectional emergency obstetric and newborn care assessments. BMC Pregnancy Childbirth 2021; 21: 1-1.

https://doi.org/10.1186/s12884-021-04008-9

4. Zhang J, Troendle J, Reddy UM, Laughon SK, Branch DW. Contemporary cesarean delivery practice in the United States. Am J Obstet Gynecol 2010; 203(4): 326-e1.

https://doi.org/10.1016/j.ajog.2010.06.058

5. Chamagne M, Richard MB, Vallee A, Tahiri J, Renevier B, Dahlhoff S, et al. Trial of labour versus elective caesarean delivery for estimated large for gestational age foetuses after prior caesarean delivery: a multicenter retrospective study. BMC Pregnancy Childbirth 2023; 23(1): 388.

https://doi.org/10.1186/s12884-023-05688-1

6. Trojano G, Damiani GR, Olivieri C, Villa M, Malvasi A, Alfonso R, et al. VBAC: antenatal predictors of success. Acta Biomed 2019; 90(3): 300-309.

https://doi.org/10.23750/abm.v90i3.7623

7. Sabol B, Denman MA, Guise JM. Vaginal birth after cesarean: an effective method to reduce cesarean. Best Pract Res Clin Obstet Gynaecol 2015; 58(2): 309-319.

https://doi.org/10.1097/GRF.0000000000000101

8. Melamed N, Segev M, Hadar E, Peled Y, Wiznitzer A, Yogev Y. Outcome of trial of labor after cesarean section in women with past failed operative vaginal delivery. Am J Obstet Gynecol 2013; 209(1): 49-e1.

https://doi.org/10.1016/j.ajog.2013.03.010

9. Bozkurt M, Yumru AE, Şahin L. Pelvic floor dysfunction, and effects of pregnancy and mode of delivery on pelvic floor. Trop J Obstet Gynaecol 2014; 53(4): 452-458.

https://doi.org/10.1016/j.tjog.2014.08.001

10. Ye L, Cao W, Yao J, Peng G, Zhou R. Systematic review of the effects of birth spacing after cesarean delivery on maternal and perinatal outcomes. Int J Gynecol Obstet 2019; 147(1): 19-28.

https://doi.org/10.1002/ijgo.12895

11. Siddiqui SA. Obstetric factors for unsuccessful trial of labor in second-order birth following previous cesarean. Ann Saudi Med 2013; 33(4): 356-362.

https://doi.org/10.5144/0256-4947.2013.356

12. Nkwabong E, Fomulu JN, Djomkam Youmsi FL. Trial of labor after cesarean section among women with unique lower segment scarred uterus and fetal weight> 3500 g: prognostic factors for a safe vaginal delivery. J Obstet Gynaecol India 2016; 66: 202-2026.

https://doi.org/10.1007/s13224-015-0835-1

13. Gambacorti‐Passerini Z, Gimovsky AC, Locatelli A, Berghella V. Trial of labor after myomectomy and uterine rupture: a systematic review. Acta Obstet Gynecol Scand 2016; 95(7): 724-734. https://doi.org/10.1111/aogs.12920

14. Trojano G, Damiani GR, Olivieri C, Villa M, Malvasi A, Alfonso R, et al. VBAC: antenatal predictors of success. Acta Biomed 2019; 90(3): 300-309. https://doi.org/10.23750/abm.v90i3.7623

15. Yamani-Zamzami TY. Delivery outcomes at term after one previous cesarean section. Saudi Med J 2007; 28(12): 1845-11849.

16. Peled T, Sela HY, Joseph J, Martinotti T, Grisaru-Granovsky S, Rottenstreich M. Factors associated with failed trial of labor after cesarean, among women with twin gestation—a multicenter retrospective cohort study. J Clin Med 2022; 11(15): 4256.

https://doi.org/10.3390/jcm11154256

17. Dombrowski M, Illuzzi JL, Reddy UM, Lipkind HS, Lee HC, Lin H, et al. Trial of Labor After Two Prior Cesarean Deliveries: Patient and Hospital Characteristics and Birth Outcomes. Obstet Gynecol 2020; 136(1): 109-117.

https://doi.org/10.1097/AOG.0000000000003845

18. Shi H, Li S, Lv J, Wang HH, Hou Q, Jin Y. Maternal and neonatal characteristics associated with clinical outcomes of TOLAC from 2012–20 in the USA: Evidence from a retrospective cohort study. eClin Med 2022: 1; 54.

https://doi.org/10.1016/j.eclinm.2022.101681

Downloads

Published

28-02-2026

Issue

Section

Original Articles

How to Cite

1.
yaqub U, Imran A, Ashraf V, Siraj A, Aslam Q ul A, Tariq M. Navigating Trial of Labor after Cesarean Section: Insight into Unfavorable Results. Pak Armed Forces Med J [Internet]. 2026 Feb. 28 [cited 2026 Mar. 5];76(1):120-5. Available from: https://pafmj.org/PAFMJ/article/view/12841