Comparison of Intravenous Tramadol vs Intravenous Morphine in Attenuation of Hemodynamic Stress response to Laryngoscopy and Endotracheal Intubation in Laparoscopic Cholecystectomy

Authors

  • Basit Mehmood Khan Combined Military Hospital, Peshawar/National University of Medical Sciences (NUMS) Pakistan
  • Farrukh Ayub Combined Military Hospital, Mardan/National University of Medical Sciences (NUMS) Pakistan
  • Sundas Shoukat Combined Military Hospital, Peshawar/National University of Medical Sciences (NUMS) Pakistan
  • Syed Khurram Naseer Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Umer Hayat Pakistan Air Force Hospital, Shorkot Pakistan
  • Junaid Zafar Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v73i2.9199

Keywords:

Tracheal intubation, Intravenous Morphine, Hemodynamic stress response

Abstract

Objective: To compare the efficacy of intravenous Tramadol and intravenous Morphine in attenuation of hemodynamic stress response to laryngoscopy and endotracheal intubation in laparoscopic cholecystectomy.

Study Design: Quasi-experimental study

Place and Duration: Department of Anesthesia, Combined Military Hospital, Mardan Pakistan, from Jun 2021 to Jun 2022.

Methodology: A total of 136 patients were involved in the research. These patients were divided via a lottery method into two groups i.e., Group-T (Tramadol) and Group-M (Morphine) with 68 patients in each group. Patients aged 20-50 years planned for laparoscopic cholecystectomy with American Society of Anesthesiologists (ASA) Grade I or Grade II were included in the study.

Results: Out of a total of 136 patients with equal distribution of 68(50%) patients in each group. Patients with ASA– I Grade from Group–T and Group-M were 52(76.5%) and 41(60.1%), respectively; however, ASA–II Grade patients were 16(23.5%) from Group–T and 27(39.7%) from Group–M. In this study, intravenous Tramadol was effective in 48(70.5%) out of 68 patients, while intravenous Morphine was effective in 60(88.24%) patients, with a p-value of 0.01.

Conclusion: This study concluded that intravenous Morphine is more effective in attenuating hemodynamic stress response to laryngoscopy and endotracheal intubation in laparoscopic cholecystectomy than intravenous Tramadol.

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Published

03-05-2023

Issue

Section

Original Articles

How to Cite

1.
Khan BM, Ayub F, Shoukat S, Naseer SK, Hayat U, Zafar J. Comparison of Intravenous Tramadol vs Intravenous Morphine in Attenuation of Hemodynamic Stress response to Laryngoscopy and Endotracheal Intubation in Laparoscopic Cholecystectomy. Pak Armed Forces Med J [Internet]. 2023 May 3 [cited 2024 Jun. 18];73(2):535-38. Available from: https://pafmj.org/PAFMJ/article/view/9199