COMPARISON OF EFFICACY OF CELECOXIB (SELECTIVE NON STEROIDAL ANTI INFLAMMATORY DRUG) VERSUS NAPROXEN (NON SELECTIVE NON STEROIDAL ANTI INFLAMMATORY DRUG) FOR POST ENDODONTIC PAIN

  • Beenish Abbas Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Sana Abbas Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Madiha Sattar Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Shoaib Rahim Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Sidra Amir Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Keywords: Celecoxib, Naproxen, Post, endodontic pain

Abstract

Objective: To determine efficacy of celecoxib (selective cyclooxygenase - II non steroidal anti inflammatory drug) versus naproxen (non selective cyclooxygenase – I & II non steroidal anti inflammatory drug) for post endodontic pain.

Study Design: Comparative prospective study.

Place and Duration of Study: The study was executed at Department of Operative Dentistry, Armed Forces Institute of Dentistry (AFID), from Apr 2017 to Apr 2018.

Methodology: Total 961 patients (group A Celecoxib n=482 and group B Naproxen n=479) requiring root canal therapy were selected. The patient’s record regarding his pain perception using a visual analog scale (VAS) at 6 hours after root canal therapy was recorded. Descriptive statistics were used to calculate mean ± SD. for age and pain, before the procedure and after 6 hours of procedure in each groups.

Results: Total 961 patients were enrolled for the subject study out of which celecoxib group constituted 482 (50.1%) and naproxen group constituted 479 (49.8%) of total. 244 (50.6%) patients in group A (Celecoxib) exhibited adequate pain relief with no gastric discomfort and side effects whereas 195 (40.7%) patients had satisfactory pain relief in group B (Naproxen), however experienced gastric side effects such as nausea and dyspepsia.

Conclusion: Celecoxib was found to be more effective in post – endodontic pain with minimal gastric symptoms, when compared to Naproxen.

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Published
2020-08-20
How to Cite
Abbas, B., Abbas, S., Sattar, M., Rahim, S., & Amir, S. (2020). COMPARISON OF EFFICACY OF CELECOXIB (SELECTIVE NON STEROIDAL ANTI INFLAMMATORY DRUG) VERSUS NAPROXEN (NON SELECTIVE NON STEROIDAL ANTI INFLAMMATORY DRUG) FOR POST ENDODONTIC PAIN. Pakistan Armed Forces Medical Journal (PAFMJ), 70(4), 1133-37. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/5107
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Original Articles