Salicylic Acid Versus Glycolic Acid Peel in Active Acne

  • Kanza Aftab Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Nadia Iftikhar Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Majid Hussain Combined Military Hospital Abbottabad/ National University of Medical Sciences (NUMS) Pakistan
  • Zarnab Zainab Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Maimoona Mumtaz Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Shanza Obaid Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Keywords: Acne vulgaris, Glycolic acid peel, Salicylic acid peel

Abstract

Objective: To compare the efficacies of Salicylic acid and Glycolic acid peel in patients with active acne.

Study Design: Quasi-experimental study.

Setting and Duration of Study: Department of dermatology, Pak Emirates Military Hospital, (PEMH) Rawalpindi Pakistan, Dec 2018 to Jan 2020.

Methodology: A total of 300 patients with active acne were included in this study. Patients were randomized into groups by lottery method. Group-A was given 30% Salicylic acid, while Group-B was given 70% Glycolic acid to control active acne. A grading system developed by Hayashi et al, was used to assess the response. A score less than six after 12 weeks was considered a positive response. In addition, the type of treatment and other factors were compared in the patients with and without a positive response after the designated treatment.

Results: Out of 300 patients with active acne included in the study, 172 (57.3%) had a positive response, while 128 (42.7%) had not achieved a positive response after the twelve-week treatment. Use of 30% Salicylic acid, lesser duration of acne and more minor age of the patients had a statistically significant relationship with a positive response in the study population (p-value 0.010, 0.005 and 0.001, respectively).

Conclusion: A significant number of patients did not respond to standard therapy of acne vulgaris. However, chances of achieving a positive response increase with 30% Salicylic acid instead of 70% Glycolic acid, lesser duration of acnes and young patients have more chances of getting a positive response at the end of the therapy.

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Published
2022-06-26
How to Cite
Aftab, K., Iftikhar, N., Hussain, M., Zainab, Z., Mumtaz, M., & Obaid, S. (2022). Salicylic Acid Versus Glycolic Acid Peel in Active Acne. PAFMJ, 72(3), 896-99. https://doi.org/10.51253/pafmj.v72i3.4338
Section
Original Articles

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