Salicylic Acid Versus Glycolic Acid Peel in Active Acne

Authors

  • Kanza Aftab Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Nadia Iftikhar Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Majid Hussain Combined Military Hospital Abbottabad/ National University of Medical Sciences (NUMS) Pakistan
  • Zarnab Zainab Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Maimoona Mumtaz Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Shanza Obaid Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v72i3.4338

Keywords:

Acne vulgaris, Glycolic acid peel, Salicylic acid peel

Abstract

Objective: To compare the efficacies of Salicylic acid and Glycolic acid peel in patients with active acne.

Study Design: Quasi-experimental study.

Setting and Duration of Study: Department of dermatology, Pak Emirates Military Hospital, (PEMH) Rawalpindi Pakistan, Dec 2018 to Jan 2020.

Methodology: A total of 300 patients with active acne were included in this study. Patients were randomized into groups by lottery method. Group-A was given 30% Salicylic acid, while Group-B was given 70% Glycolic acid to control active acne. A grading system developed by Hayashi et al, was used to assess the response. A score less than six after 12 weeks was considered a positive response. In addition, the type of treatment and other factors were compared in the patients with and without a positive response after the designated treatment.

Results: Out of 300 patients with active acne included in the study, 172 (57.3%) had a positive response, while 128 (42.7%) had not achieved a positive response after the twelve-week treatment. Use of 30% Salicylic acid, lesser duration of acne and more minor age of the patients had a statistically significant relationship with a positive response in the study population (p-value 0.010, 0.005 and 0.001, respectively).

Conclusion: A significant number of patients did not respond to standard therapy of acne vulgaris. However, chances of achieving a positive response increase with 30% Salicylic acid instead of 70% Glycolic acid, lesser duration of acnes and young patients have more chances of getting a positive response at the end of the therapy.

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Published

26-06-2022

Issue

Section

Original Articles

How to Cite

1.
Aftab K, Iftikhar N, Hussain M, Zainab Z, Mumtaz M, Obaid S. Salicylic Acid Versus Glycolic Acid Peel in Active Acne. Pak Armed Forces Med J [Internet]. 2022 Jun. 26 [cited 2024 Jun. 23];72(3):896-99. Available from: https://pafmj.org/PAFMJ/article/view/4338