THE EFFECT OF ENERGY DRINK ON THE PANCREAS OF WISTAR ALBINO RATS – A MICROSCOPIC STUDY

  • Fatima Rehman Bahria University Medical and Dental College, Karachi Pakistan
  • Zia Ul Islam Liaquat National Hospital and Medical College, Karachi Pakistan
  • Uzma Hameed Dow International Dental College, Karachi Pakistan
  • Sadia Rehman Bahria University Medical and Dental College, Karachi Pakistan
Keywords: Energy drink, Hemorrhage, Mononuclear cells sequestration, Vascular congestion

Abstract

Objective: To observe the microscopic changes on the pancreas of Wistar Albino rats, following the oral administration of energy drink.

Study Design: Laboratory based experimental study.

Place and Duration of Study: This study was conducted at the department of Anatomy, Basic medical Sciences Institute (BMSI), Jinnah Postgraduate medical Center (JPMC) Karachi, in October 2018 for a period of four weeks. Methodology: Thirty adult, healthy male Wistar Albino rats equally divided into three groups were used in the study. Group A served as control, group B as treated with energy drink at a dose of 7.5ml/day orally and group C treated with energy drink at a dose of 15ml/day orally, for a period of 4 weeks.

Results: The Haematoxylin and Eosin (H&E) stained sections of pancreatic tissue have shown marked pathological changes. Dilated and congested blood vessels were a significant finding in the treated tissues. Sequestration of mononuclear cells was also found on microscopy depicting the inflammatory process in the pancreas of treated animals.

Conclusion: Energy drink consumption caused significant injurious and deleterious effects on the pancreas of the Albino rats.

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Published
2020-04-30
How to Cite
Rehman, F., Islam, Z., Hameed, U., & Rehman, S. (2020). THE EFFECT OF ENERGY DRINK ON THE PANCREAS OF WISTAR ALBINO RATS – A MICROSCOPIC STUDY. Pakistan Armed Forces Medical Journal, 70(2), 524-28. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/4223
Section
Original Articles