EFFICACY OF SACCHAROMYCES BOULARDII IN THE MANAGEMENT OF ACUTE WATERY DIARRHEA

  • Misbah Munir Mekran Medical College Turbat Pakistan
  • Sajid Ali Shah Combined Military Hospital Skardu/National University of Medical Sciences (NUMS) Pakistan
  • Saeed Zaman Combined Military Hospital Kharian/National University of Medical Sciences (NUMS) Pakistan
  • Lutfullah Goheer Combined Military Hospital Multan/National University of Medical Sciences (NUMS) Pakistan
  • Sana Bushra Civil Hospital Quetta Pakistan
  • Sajjad Ahmad Khan Fauji Foundation Hospital Peshawar Pakistan
Keywords: Acute watery diarrhea, Children, Dehydration, Probiotics, Saccrharomyces boulardii

Abstract

Objective: To determine the Efficacy of probiotic (saccharomyces boulardii) in children (2 months to 5 years) with acute watery diarrhea.

Study Design: Comparative cross sectional study.

Place and Duration of Study: This study was carried out in the department of pediatrics, Combined Military Hospital, Quetta, from Jan 2017 to Jun 2018.

Methodology: All children (2 months to 5 years) with acute watery diarrhea presenting within 24 hour of illness with no dehydration and some dehydration were enrolled and divided into two groups, study group and control group. Efficacy was assessed by reduced frequency of stools(less than 3 per day) and duration during the study period.

Results: Mean age of the children in probiotic saccharomyces boulardii group was 3.42 ± 1.36 years, while mean age in control group was 3.91 ± 1.16 years (p-value 0.002). Significant difference was also observed in duration of stool and frequency of stool at day 1-5 (p-value <0.05). Statistically significant difference was observed among children in probiotic sacchramyces boulardii group 114 (53%) as compared to controls 101 (47%) (p-value 0.021).

Conclusion: The Efficacy of probiotic (saccrharomyces boulardii) was found satisfactory in children (2 months to 5 years) with acute watery diarrhea. In children with acute watery diarrhea saccrharomyces boulardii may be recommended for better outcome.

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Published
2021-04-30
How to Cite
Munir, M., Shah, S., Zaman, S., Goheer, L., Bushra, S., & Khan, S. (2021). EFFICACY OF SACCHAROMYCES BOULARDII IN THE MANAGEMENT OF ACUTE WATERY DIARRHEA. PAFMJ, 71(2), 686-89. https://doi.org/10.51253/pafmj.v71i2.3742
Section
Original Articles