Effect of Posterior Subtenon Triamcinolone Acetonide in Refractory Diabetic Macular Edema

  • Muhammad Kashif Habib Al Shifa Trust Eye Hospital, Rawalpindi Pakistan
  • Rubab Shafqat Riphah International University, Islamabad Pakistan
  • Zeeshan Khan Oozeerkhan Al Aleem Medical College, Lahore Pakistan
  • Anwar Ahmed Gul Pakistan Institute of Medical Sciences, Islamabad Pakistan
  • Nighat Jabeen Quetta Institute of Medical Sciences, Quetta Cantt Pakistan
  • Muhammad Usman Sadiq Mohi-ud-Din Islamic Medical College, Mirpur, Azad Jammu and Kashmir Pakistan
Keywords: Central macular thickness, Intraocular pressure, Intravitreal bevacizumab, Posterior subtenon triamcinolone, Refractory diabetic macular edema

Abstract

Objectives: To see the effect of Posterior Subtenon Triamcinolone Acetonide (PSTT) injection in refractory Diabetic Macular Edema (DME).

Study Design: Quasi-Experimental Study.

Place and Duration of Study: Retina Clinic, Al-Shifa Trust Eye Hospital, Rawalpindi, from Jun to Dec 2018.
Methodology: Patients with Clinically Significant Macular Edema (CSME), with Central Macular Thickness (CMT) >300 microns and those who did not respond to three consecutive Intra-Vitreal Bevacizumab (IVB) injections were included. Posterior Subtenon Triamcinolone Acetonide (PSTT) was administered by a single retina fellow using the same protocol. Each patient’s best-corrected visual acuity (BCVA), Intra-ocular pressure (IOP) and Central Macular Thickness (CMT) were evaluated on the day of Posterior Subtenon Triamcinolone Acetonide (PSTT) injection and again at 1, 3 and 6 months.

Results: Out of 52 patients (104 eyes), 16 females and 36 males were present. The mean age was 57.67±9.35 years. Out of 52 right eyes, the mean Central Macular Thickness (CMT) at the first visit was 388.83±172.04 µm, 332.81 ± 144.69 µm after one month, 292.81±147.59µm after six months of Posterior Subtenon Triamcinolone Acetonide (PSTT) Injection. Similarly, for 52 left eyes mean Central Macular Thickness (CMT) at the first visit is 375.79±160.81 µm, 364.52 ± 167.95 µm after one month and 323.37±155.74 µm after six months. Similar results were observed for IOP and BCVA.

Conclusion: Posterior Subtenon Triamcinolone (PSTT) injections are effective in diabetic macular oedema, which does not respond to intravitreal anti-VEGF (IVB) therapy.

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Published
2022-08-31
How to Cite
Habib, M., Shafqat, R., Oozeerkhan, Z., Gul, A., Jabeen, N., & Sadiq, M. (2022). Effect of Posterior Subtenon Triamcinolone Acetonide in Refractory Diabetic Macular Edema. Pakistan Armed Forces Medical Journal (PAFMJ), 72(4), 1211-14. https://doi.org/10.51253/pafmj.v72i4.3597
Section
Original Articles