DIAGNOSTIC ACCURACY OF MAGNETIC RESONANCE IMAGING IN DIAGNOSING BONE TUMORS KEEPING HISTOPATHOLOGICAL CORRELATION AS GOLD STANDARD

Role of MRI in Bone tumors

Abstract

Objective: To determine the diagnostic accuracy of magnetic resonance imaging in diagnosing bone tumors
keeping histopathological as correlation gold standard.

Study Design: Descriptive cross-sectional study.

Place and Duration of Study: Departments of Radiology, Orthopedics and Pathology of Pakistan Institute of
Medical Sciences, Islamabad, from Jan 2018 to Jan 2019.

Methodology: All the patients who had complain of bone deformity or pain with high suspicion of neoplastic
pathology involving bone and soft tissue on radiograph were included in study. Patients were first diagnosed on conventional radiography followed by magnetic resonance imaging. Magnetic resonance imaging with contrast was done on Phillips 1.5 tesla machine. T1W, T2W, STIR images, Fat suppressed, PD spair and post contrast T1W images were obtained. Positive magnetic resonance imaging findings which were noted were; marrow involvement, cortical break, soft tissue involvement, joint involvement, neurovascular bundle involvement and post contrast enhancement on T1W imaging. Then bone biopsy was performed. The removed bone was sent for histopathological examination in all cases. The histopathological reports were collected. The results were entered in structured proformas. Data was collected after the informed consent. All the data was entered and analyzed using SPSS version-23.

Results: Fifty patients of both genders were recruited during our study duration. 32 (64.0%) were male while 18
(36.0%) were female patients. Mean age of the patient was 54.5 ± 14.3 years with range 18 to 80 years. Among the benign tumors vertebral hemangiomas were most commonly found 5 (10.0%) followed by osteochondroma which was 4 (8.0%), while among malignant........