EFFECT OF LEVODOPA ON PERSONALITY DISTURRBANCES AND DYSEXECUTIVE SYMPTOMS IN PATIENTS WITH IDIOPATHIC PARKINSON’S DISEASE

  • Amara Gul The Islamia University of Bahawalpur, Bahwalpur Pakistan
  • Javed Yousaf The Islamia University of Bahawalpur, Bahwalpur Pakistan
Keywords: Behavior, Levodopa, Parkinson’s disease

Abstract

Objective:

To assess effects of levodopa (L-dopa) on personality disturbances and dysexecutive symptoms in patients with idiopathic Parkinson’s disease (PD).

Study Design: Prospective test-retest design.

Place and Duration of Study: Bahawal Victoria Hospital and Civil Hospital, Bahawalpur, Pakistan during June 2016 to June 2017.

Material and Methods:

Informants of sixty patients with idiopathic PD rated changes in personality on lowa scale of personality change and dysexecutive symptoms on dysexecutive questionnaire after three months of L-dopa treatment. Informants and clinical psychologist who collected data from informants were both blind to the objective of the study.

Results:

Personality disturbances and dysexecutive functioning (dysexecutive symptoms, inhibition, social regulation) were significantly reduced post L-dopa treatment.

Conclusion:

L-dopa is an effective treatment for bringing positive personality and cognition related changes in patients with idiopathic PD.

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Published
2018-12-31
How to Cite
Gul, A., & Yousaf, J. (2018). EFFECT OF LEVODOPA ON PERSONALITY DISTURRBANCES AND DYSEXECUTIVE SYMPTOMS IN PATIENTS WITH IDIOPATHIC PARKINSON’S DISEASE. Pakistan Armed Forces Medical Journal, 68(6), 1775-79. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/2613
Section
Short Communication