NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY

  • Madiha Ahmed Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Yasrab Armed Forces Institute of Urology/ National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Arshad Khushdil Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Khadija Qamar Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Zeeshan Ahmed Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
Keywords: Antimicrobial sensitivity, Bacteriological profile, Multi drug resistance, Neonatal sepsis

Abstract

Objective:

To study the spectrum and antimicrobial sensitivity of bacterial pathogens causing neonatal sepsis, in neonatal intensive care unit (NICU) of Pak Emirates Military Hospital, Rawalpindi.

Study Design: Prospective cross sectional study.

Place and Duration of Study: This was a prospective cross sectional study, conducted at NICU of Military Hospital, Rawalpindi, from Jul 2017 to Dec 2017.

Material and Methods:

All neonates admitted to our department who underwent evaluation for sepsis, from Jul 2017 to Dec 2017.

Results:

Out of 2,480 admitted neonates, 733 were suspected with sepsis, making an incidence of suspected neonatal sepsis to be 29.5%. 421 (57.4%) babies were suspected with early onset sepsis (EOS) and 312 (42.6%) with late onset sepsis (LOS). Majority of the babies (70.3%) were preterm. In 281 (11.3%) neonates, blood culture came out to be positive. 73/281 neonates with culture proven sepsis died making a mortality rate of 25.9%. Gram negative bacilli were most predominant among isolated bacteria. Most of the organisms showed resistance to the first line antibiotics.

Conclusion:

Sepsis has a high mortality rate in neonates admitted to our department. Gram negative organisms are the most common cause. Most of the isolated organisms are resistant to empirical antibiotics.

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Published
2018-12-31
How to Cite
Ahmed, M., Yasrab, M., Khushdil, A., Qamar, K., & Ahmed, Z. (2018). NEONATAL SEPSIS IN A TERTIARY CARE HOSPITAL: BACTERIOLOGICAL PROFILE AND ITS ANTIBICROBIAL SENSITIVITY. Pakistan Armed Forces Medical Journal, 68(6), 1654-58. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/2566

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