EFFECT OF PASSIVE SMOKING ON THE LEVELS OF PREGNANCY ASSOCIATED PLASMA PROTEIN –A IN NORMAL RATS

Passive Smoking on the Levels of Pregnancy Associated Plasma Protein

  • Dr Amena Rahim Department of Biochemistry, Army Medical College Rawalpindi
  • Abdul Khaliq Naveed Army Medical College Rawalpindi
  • Maujid Masood Malik Army Medical College Rawalpind
  • Tehmina Qamar Army Medical College Rawalpind
Keywords: Pregnancy associated plasma protein- A, Cigarette smoke, Sprague-Dawley strain

Abstract

Objectives: To measure the levels of pregnancy associated plasma protein- A (PAPPA-A) in normal rats exposed to cigarette smoke.

Study Design: Experimental interventional study Place and Duration of Study: Army Medical College, Rawalpindi, in collaboration with national institute of health (NIH), Islamabad. Total duration was of 4 weeks. Material and Method: Sixty albino rats of Sprague- Dawley strain weighing 200-250 gm, divided into two groups. Both the groups were kept in identical chambers. One group of 30 rats was further exposed to passive cigarette smoke for 4 weeks.

Results: No increase was observed in the levels of serum PAPP-A of both the groups: Passive smokers and not exposed to passive smoking i .e. P > 0.05. Conclusions: Smoking does not increase the levels of PAPP-A.

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Published
2010-03-31
How to Cite
Rahim, D. A., Naveed, A., Malik, M., & Qamar, T. (2010). EFFECT OF PASSIVE SMOKING ON THE LEVELS OF PREGNANCY ASSOCIATED PLASMA PROTEIN –A IN NORMAL RATS. Pakistan Armed Forces Medical Journal, 60(1), 13-6. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/121
Section
Original Articles