A HISTOLOGICAL STUDY OF BOWMAN’S GLANDS IN HUMAN OLFACTORY MUCOSA
Keywords:Olfactory mucosa, Bowman’s glands, human
Background: The histology of olfactory mucosa has been previously studied under light and electron microscope. There are marked geographical differences between Pakistan and other countries where most of the research on olfactory epithelium has been conducted.
Objectives: To study morphology and quantitative analysis of Bowman’s glands in human olfactory mucosa in Pakistani population.
Study Design: An observational study.Place and Duration of Study: This research was done in the Anatomy Department, A M College, Rawalpindi. The duration of study was two years from January 2001 to December 2003.
Materials and Methods: Enbloc specimens were obtained from 20 autopsy cases. After decalcification, they were processed, stained with haematoxylin and eosin (H&E) and seen under light microscope. The olfactory mucosa was observed in the roof, medial and lateral walls of both nasal cavities. The type of glandular tissue and its morphology was observed
Results: The olfactory epithelium was morphologically pseudostraified columnar with a characteristic lamina propria containing numerous olfactory nerve fascicles and Bowman’s glands, observed in the roof, medial and lateral walls of both nasal cavities. The secretory acini were almost circular in cross section and measured 20 to 25 µm in diameter. The secretory cells (7-10 µm) were pyramidal in shape, with rounded darkly stained nuclei lying in the basal half of the cells. The ducts were seen leading from the glands onto epithelial surface. Mean number of serous acini when compared in the roof, medial and lateral walls of right and left nasal cavities was statistically insignificant.Conclusion: Olfactory mucosa was lined with pseudostratified columnar epithelium. The secretory acini of Bowman’s glands were almost circular in cross section and cells were pyramidal in shape. Mean number of serous acini when compared in the roof, medial and lateral walls of right and left nasal cavities was statistically insignificant.