Comparison of Various Factors in Patients of Essential Hypertension with and Without Vitamin D Deficiency Presenting To Family Practice

Authors

  • Namra Nazir Department of Family Medicine, Pak Emirates Military Hospital Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Sadaf Nawaz Department of Family Medicine, Pak Emirates Military Hospital Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Adil Khan Department of Family Medicine, Pak Emirates Military Hospital Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Simra Tanvir Department of Family Medicine, Pak Emirates Military Hospital Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Hadia Tahir Department of Family Medicine, Pak Emirates Military Hospital Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
  • Ayesha Nudrat Department of Family Medicine, Pak Emirates Military Hospital Rawalpindi/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75iSUPPL-2.9941

Keywords:

Family medicine; Hypertension; Lipid profile; Vitamin D.

Abstract

Objective: To compare various factors in patients of hypertension with and without Vitamin D Deficiency managed at family medicine department of our hospital.

Study Design: Comparative cross-sectional study

Place and Duration of Study: Department of Family Medicine, Pak Emirates Military hospital, Rawalpindi Pakistan, From September 2022 to November 2022.

Methodology: Patients of hypertension presenting at family medicine department without having any other metabolic illness were recruited in the study. Baseline investigations were carried out in all patients along with Vitamin D levels. Patients were divided into two groups for the sake of comparison as with and without vitamin D deficiency. Factors like age, gender, deranged lipid profile parameters and body mass index were compared in both the study groups.

Results:  Out of 206 patients of hypertension included in the study, 144(69.9%) were male while 62(30.1%) were female. Mean age of the study participants reporting at family medicine department was 46.06±9.65 years. Out of two study groups used for comparison, 84(40.7%) of the patients had Vitamin D levels within range while 122(59.3%) had deficient vitamin levels. Statistical analysis revealed that deranged lipid profile parameters and high body mass index were found statistically significantly (p-value <0.05) more in group of patients having Vitamin D deficiency as compared to those who did not have vitamin D deficiency suffering from hypertension managed at family medicine department.

Conclusion: Vitamin D deficiency was a common finding in patients managed for hypertension at family medicine department. Deranged lipid profile parameters and being overweight or obese were the 

Downloads

Download data is not yet available.

References

Sharma JR, Mabhida SE, Myers B, Apalata T, Nicol E, Benjeddou M, et al. Prevalence of Hypertension and Its Associated Risk Factors in a Rural Black Population of Mthatha Town, South Africa. Int J Environ Res Public Health 2021; 18(3): 1215. https://doi.org/ 10.3390/ijerph18031215

Riaz M, Shah G, Asif M, Shah A, Adhikari K, Abu-Shaheen A. Factors associated with hypertension in Pakistan: A systematic review and meta-analysis. PLoS One 2021; 16(1): e0246085. https://doi.org/ 10.1371/journal.pone.0246085

Taher ZA, Khayyat WW, Balubaid MM, Tashkandi MY, Alamoudi SM, Kinsara AJ. Complications of White-coat Hypertension Compared to a Normotensive and Hypertensive Population. Heart Views. 2021; 22(1): 8-12

https://doi.org/ 10.4103/HEARTVIEWS.HEARTVIEWS_64_20

Ott C, Schmieder RE. Diagnosis and treatment of arterial hypertension 2021. Kidney Int 2021: S0085-2538(21)01023-1.

https://doi.org/ 10.1016/j.kint.2021.09.026

Sizar O, Khare S, Goyal A, et al. Vitamin D Deficiency. [Updated 2020 Jul 21]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK532266/

Amrein K, Scherkl M, Hoffmann M, et al. Vitamin D deficiency 2.0: an update on the current status worldwide [published online ahead of print, 2020 Jan 20]. Eur J Clin Nutr 2020; 4(3)1-16. https://doi.org/10.1038/s41430-020-0558-y

Bae JM. Circulating 25-hydroxyvitamin D levels and hypertension risk after adjusting for publication bias. Clin Hypertens. 2022; 28(1): 15. Published 2022

https://doi.org/10.1186/s40885-022-00196-4

Karadeniz Y, Özpamuk-Karadeniz F, Ahbab S, Ataoğlu E, Can G. Vitamin D Deficiency Is a Potential Risk for Blood Pressure Elevation and the Development of Hypertension. Medicina (Kaunas) 2021; 57(12): 1297.

https://doi.org/ 10.3390/medicina57121297

Ke L, Mason RS, Mpofu E, Vingren JL, Li Y, Graubard BI et al. Hypertension and other cardiovascular risk factors are associated with vitamin D deficiency in an urban Chinese population: A short report. J Steroid Biochem Mol Biol 2017; 173: 286-291. https://doi.org/10.1016/j.jsbmb.2016.11.011

Rana MA, Javed M, Zartash S, Alam H. Prevalence of vitamin D deficiency in patients with chronic diseases like Diabetes and Hypertension presenting to medicine clinic in BBahria international Hospital, Lahore, Pakistan. Pak Postgrad Med J 2019; 30(2): 52-54.

Vatakencherry RMJ, Saraswathy L. Association between vitamin D and hypertension in people coming for health check up to a tertiary care centre in South India. J Family Med Prim Care 2019; 8(6): 2061-2067.

https://doi.org/10.4103/jfmpc.jfmpc_236_19

Gani LU, How CH. PILL Series. Vitamin D deficiency. Singapore Med J 2015; 56(8): 433-437.

https://doi.org/10.11622/smedj.2015119

Solnica B, Sygitowicz G, Sitkiewicz D, Cybulska B, Jóźwiak J, Odrowąż-Sypniewska G, et al. 2020 Guidelines of the Polish Society of Laboratory Diagnostics (PSLD) and the Polish Lipid Association (PoLA) on laboratory diagnostics of lipid metabolism disorders. Arch Med Sci 2020; 16(2): 237-252. https://doi.org/10.5114/aoms.2020.93253

Weir CB, Jan A. BMI Classification Percentile And Cut Off Points. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2022.

Alghamdi SJH, Omer EOM, Zafar M, Herzallah HKI. Association of Vitamin D Deficiency with Cardiovascular Disease Among Saudi Patients in Saudi Arabia. Int J Prev Med 2020; 11: 191. https://doi.org/ 10.4103/ijpvm.IJPVM_349_19

Ong MW, Tan CH, Cheng AKS. Prevalence and Determinants of Vitamin D Deficiency Among the Overweight and Obese Singaporeans Seeking Weight Management Including Bariatric Surgery: a Relationship with Bone Health. Obes Surg 2018; 28(8): 2305-2312. https://doi.org/10.1007/s11695-018-3142-y

Skaaby T, Husemoen LL, Pisinger C, Jørgensen T, Thuesen BH, Fenger M et al. Vitamin D status and changes in cardiovascular risk factors: a prospective study of a general population. Cardiology 2012; 123(1): 62-70.

https://doi.org/10.1159/000341277

Alagacone S, Verga E, Verdolini R, Saifullah SM. The association between vitamin D deficiency and the risk of resistant hypertension. Clin Exp Hypertens 2020; 42(2): 177-180. https://doi.org/ 10.1080/10641963.2019.1601204

Downloads

Published

25-03-2025

Issue

Section

Original Articles

How to Cite

1.
Nazir N, Nawaz S, Khan A, Tanvir S, Tahir H, Nudrat A. Comparison of Various Factors in Patients of Essential Hypertension with and Without Vitamin D Deficiency Presenting To Family Practice. Pak Armed Forces Med J [Internet]. 2025 Mar. 25 [cited 2025 Apr. 6];75(SUPPL-2):S285-S289. Available from: https://pafmj.org/PAFMJ/article/view/9941