Diagnostic Accuracy of Fetal Middle Cerebral Artery Peak Systolic Velocity in the Detection of Fetal Anaemia Keeping Neonatal Hae Moglobin Estimation at Birth as the Gold Standard

Authors

  • Saira Noreen Department of Radiology, Combined Military Hospital Quetta/National University of Medical Sciences (NUMS) Pakistan
  • Nisar Ahmed Armed Forces Institute of Radiology & Imaging/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Usman Khan Department of Radiology, Combined Military Hospital Quetta/National University of Medical Sciences (NUMS) Pakistan
  • Atiq ur Rehman Salehria Armed Forces Institute of Radiology & Imaging/National University of Medical Sciences (NUMS) Rawalpindi Pakistan
  • Muhammad Zeeshan Ali Armed Forces Institute of Radiology & Imaging/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

DOI:

https://doi.org/10.51253/pafmj.v74i2.9605

Keywords:

Anaemia, Fetus, Middle cerebral artery (MCA), Neonatal haemoglobin estimation

Abstract

Objective: To assess whether monitoring the peak systolic velocity (PSV) in the middle cerebral artery (MCA) was a useful,
non-invasive method for predicting anaemia in fetuses.

Study Design: Cross-sectional study

Place and Duration of Study: Armed Forces Institute of Radiology, Rawalpindi Pakistan, from Feb and Aug 2022.

Methodology: Fifty pregnant women who did not have hydropic babies were included. The peak systolic velocity (PSV) was
measured in the middle cerebral artery (MCA). A positive result was determined when the MCA-PSV value exceeded 1.5
multiples of the median (MoM). The blood samples obtained from neonates were forwarded to the hospital laboratory to
estimate haemoglobin levels shortly after birth. The outcome of the method (MoM) was observed and subsequently compared
with neonatal haemoglobin levels.

Results: 60% of neonates were anaemic according to middle MCA-PSV while the haematology laboratory reported 74% of
neonates as anaemic according to cut-off haemoglobin of less than 13.5gm/dl. Sensitivity, specificity, positive predictive value
(PPV), negative predictive value (NPV), and accuracy of the MCA-PSV in detecting the anaemia were 93.75%, 61.1%, 81.08%,
84.62%, and 82%, respectively.

Conclusion: MCA-PSV Doppler is deemed valuable as a diagnostic technique for fetal anaemia, albeit secondary to the
primary approach of neonatal haemoglobin estimation upon birth.

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Published

29-04-2024

How to Cite

1.
Noreen S, Nisar Ahmed, Muhammad Usman Khan, Atiq ur Rehman Salehria, Muhammad Zeeshan Ali. Diagnostic Accuracy of Fetal Middle Cerebral Artery Peak Systolic Velocity in the Detection of Fetal Anaemia Keeping Neonatal Hae Moglobin Estimation at Birth as the Gold Standard. Pak Armed Forces Med J [Internet]. 2024 Apr. 29 [cited 2024 May 24];74(2):469-72. Available from: https://pafmj.org/PAFMJ/article/view/9605

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