Comparison of Dexamethasone and Local Anaesthetic Infiltration in Management of Postoperative Nausea and Vomiting in Pediatric Tonsillectom

Muhammad Shahzad  Bashir; Sana Abbas; Usman  Saqib; Shakeel  Ahmed; Adeela  Khan; Hareem  Azhar

doi:10.51253/pafmj.v75i4.9181

Authors

Muhammad Shahzad Bashir Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Sana Abbas Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Usman Saqib Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Shakeel Ahmed Department of ENT, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Adeela Khan Department of Anesthesia, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan
Hareem Azhar Department of ENT, Combined Military Hospital, Rawalpindi/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v75i4.9181

Keywords:

Corticosteroids, Dexamethasone, Local infiltration, Nausea, Pain, Postoperative, Vomiting.

Abstract

Objective: Comparison of the effectiveness of intravenous Dexamethasone and pre-incision infiltration of local anesthetic among Pediatric tonsillectomy patients in reduction of postoperative nausea, vomiting, and pain.

Study Design: Quasi-Experimental Study.

Place and Duration of Study: Combined Military Hospital, Rawalpindi, Pakistan, from Jan to Jun 2022.

Methodology: Pediatric patients aged 04 to 13 years undergoing tonsillectomy under general anesthesia were enrolled in the study. Group-A was administered intravenous Dexamethasone 0.5 mg/kg (up to 16 mg), and Group-B was administered a 24ml of local anesthesia as pre-incision infiltration.

Results: A total of 126 patients enrolled in the study, with equal distribution in each group. In the post-anesthesia recovery unit, 10(15.9%) of patients in Group-A had vomiting, whereas 2(3.2%) in Group-B experienced vomiting (p-value 0.03). After 24 hours, the PONV frequency rose to 17(27.0%) and 6(9.5% respectively, in Group-A and Group-B (p-value 0.02), with compatible results at 48 hours, 3^rd, 4^th, and 5^th day postoperatively. Group-A has shown higher consumption of postoperative analgesics in post post-anesthesia recovery unit and throughout from 1^stto 5th day. 10(16.2%) and 21(32.8%) patients in Groups A and B, respectively, were able to drink during their PACU stay (p-value 0.05).

Conclusion: Local anesthetic infiltration is an effective modality for reduction of postoperative nausea and vomiting, along with analgesic potential in Pediatric patients undergoing tonsillectomy under general anesthesia.

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