Frequency of Low Bone Mineral Density and Its Age and Gender Related   Association in Pakistani Population

Authors

  • Muhammad Farooq Department of Medicine, Combined Military Hospital, Nowshera/National University of Medical Sciences (NUMS) Pakistan
  • Sajida Shaheen Department of Pathology, Combined Military Hospital, Peshawar/National University of Medical Sciences (NUMS) Pakistan
  • Majida Farooq Department of Pathology, Combined Military Hospital, Nowshera/National University of Medical Sciences (NUMS) Pakistan
  • Hannan Zafar Combined Military Hospital, Lahore/National University of Medical Sciences (NUMS) Pakistan
  • Amna Saleem Combined Military Hospital, Nowshera/National University of Medical Sciences (NUMS) Pakistan

DOI:

https://doi.org/10.51253/pafmj.v74i3.9167

Keywords:

Bone density, Osteopenia, Osteoporosis

Abstract

Objective: To determine the frequency of low bone mineral density and its probable association with age and gender in Pakistani populations in suburban areas of Lahore.

Study Design:  Cross-sectional study

Place and Duration of Study: Combined Military Hospital, Lahore Pakistan, from Feb to May 2018.

Methodology: In this study, 249 subjects were selected through non-probability convenience sampling.  Information was endorsed in a pre-designed questionnaire after taking a brief history from all patients. The OsteoSys bone densitometer was used to calculate bone mineral density. To assess bone mineral density and the risk of osteopenia and osteoporosis, T-scores were used. In addition, to maximise accuracy and decrease the chance of error, we calibrated the machine before its use.

Results: Osteoporosis was found in 91(36.54%) and osteopenia in 146(58.63%) of participants. Only 12(4.81%) had normal bone mineral density. A significant association of decreased bone mineral density with increasing age was seen (p-value ≤ 0.001).

Conclusion: This study revealed a high frequency of low bone mineral density in both genders of the Pakistani suburban population. The frequency increased with advancing age and post-menopausal status.

Downloads

Download data is not yet available.

References

Blake GM, Fogelman I. The role of DXA bone density scans in the diagnosis and treatment of osteoporosis. Postgrad Med J. 2007; 83(982): 509-517.

https://doi.org/10.1136/pgmj.2007.057505

Sözen T, Özışık L, Başaran NÇ. An overview and management of osteoporosis. Eur J Rheumatol 2017 ; 4(1): 46-56.

https://doi.org/10.5152/eurjrheum.2016.048

Lowe NM, Ellahi B, Bano Q, Bangash SA, Mitra SR, Zaman M. Dietary calcium intake, vitamin D status, and bone health in postmenopausal women in rural Pakistan. J Health Popul Nutr 2011; 29(5): 465-470. https://doi.org/ 10.3329/jhpn.v29i5.8900

Panta S, Neupane M, Thapa SK, Sapkota K. Osteoporosis among Postmenopausal Women Attending the Orthopedics Department of a Tertiary Care Hospital: A Descriptive Cross-sectional Study. JNMA J Nepal Med Assoc 2021; 59(237): 446-449.

https://doi.org/ 10.31729/jnma.6031

Lowe NM, Mitra SR, Foster PC, Bhojani I, McCann JF. Vitamin D status and markers of bone turnover in Caucasian and South Asian postmenopausal women living in the UK. Br J Nutr 2010; 103(12): 1706-1710. https://doi.org/ 10.1017/S0007114509993850

Haris S, Jahan F, Afreen A, Ahmed H, Ahmed Z. To Determine the Risk Factors and Prevalence of Osteoporosis among Adult Pakistani Population Residing in Karachi Using Quantitative Ultrasound Technique. J Community Med Health Educ 2014; 4: 299. https://doi.org/ 10.4172/2161-0711.1000299

Khan AH, Jafri L, Ahmed S, Noordin S. Osteoporosis and its perspective in Pakistan: A review of evidence and issues for addressing fragility fractures. Ann Med Surg 2018; 29: 19-25.

https://doi.org/ 10.1016/j.amsu.2018.03.019

McClung MR, Clark AL. Osteoanabolic therapy for osteoporosis in women. Climacteric 2022; 25(1): 60-66.

https://doi.org/10.1080/13697137.2021.1953463

de Villiers TJ, Goldstein SR. Bone health 2022: an update. Climacteric 2022; 25(1): 1-3.

https://doi.org/10.1080/13697137.2021.1965408

Diez-Perez A, Naylor KE, Abrahamsen B, Agnusdei D, Brandi ML, Cooper C, et al; Adherence Working Group of the International Osteoporosis Foundation and the European Calcified Tissue Society. International Osteoporosis Foundation and European Calcified Tissue Society Working Group. Recommendations for the screening of adherence to oral bisphosphonates. Osteoporos Int 2017; 28(3): 767-774.

https://doi.org/10.1007/s00198-017-3906-6

Fatima M, Nawaz H, Kassi M, Rehman R, Kasi PM, Kassi M, et al. Determining the risk factors and prevalence of osteoporosis using quantitative ultrasonography in Pakistani adult women. Singapore Med J 2009; 50(1): 20-28.

Gupta SK. Editorial: Prevalence of Osteoporosis in Women in Buenos Aires Based on Bone Mineral Density at the Lumbar Spine and Femur. J Clin Densitom 2016; 19(4): 405-406.

https://doi.org/10.1016/j.jocd.2016.03.005

Rehman DS, Haq A, Memon I, Mahmood N, Rehman SF, Malik F. Frequency Of Osteopenia And Osteoporosis In Women Using Dual Energy X-Ray Absorptiometry Scan. Pak J Phsyiol 2021; 17(2): 27-30.

Ji MX, Yu Q. Primary osteoporosis in postmenopausal women. Chronic Dis Transl Med 2015; 1(1): 9-13.

https://doi.org/10.1016/j.cdtm.2015.02.006

Compston JE, McClung MR, Leslie WD. Osteoporosis. Lancet 2019; 393(10169): 364-376.

https://doi.org/10.1016/S0140-6736(18)32112-3

Wade SW, Strader C, Fitzpatrick LA, Anthony MS, O'Malley CD. Estimating prevalence of osteoporosis: examples from industrialized countries. Arch Osteoporos 2014; 9: 182.

https://doi.org/10.1007/s11657-014-0182-3

Kaushal N, Vohora D, Jalali RK, Jha S. Prevalence of osteoporosis and osteopenia in an apparently healthy Indian population - a cross-sectional retrospective study. Osteoporos Sarcopenia 2018; 4(2): 53-60.

https://doi.org/10.1016/j.afos.2018.04.002

Hassan AB, Tayem YI, Sadat-Ali M, Almarabheh AJ, Alawadhi A, Bu,. The estimated prevalence of osteoporosis in Bahrain: a multi-centered-based study. BMC Musculoskelet Disord 2024; 25(1): 9. https://doi.org/10.1186/s12891-023-07145-8

Downloads

Published

28-06-2024

Issue

Section

Original Articles

How to Cite

1.
Farooq M, Shaheen S, Farooq M, Zafar H, Saleem A. Frequency of Low Bone Mineral Density and Its Age and Gender Related   Association in Pakistani Population. Pak Armed Forces Med J [Internet]. 2024 Jun. 28 [cited 2024 Nov. 24];74(3):835-8. Available from: https://pafmj.org/PAFMJ/article/view/9167